Comparison of predicted T cell epitopes in porcine circovirus type 2 isolates from 2017 to 2021 and selected vaccines (EpiCC analysis) confirms the global relevance of a bivalent vaccine approach

Comparison of predicted T cell epitopes in porcine circovirus type 2 isolates from 2017 to 2021 and selected vaccines (EpiCC analysis) confirms the global relevance of a bivalent vaccine approach

Porcine circovirus type 2 (PCV2) is a globally important pathogen of swine with a high capacity for genetic change, potentially including evolution of strains less susceptible to vaccine induced immunity. Starting with DNA sequences, in silico tools can be used to predict the T cell epitope content...

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Bibliographic Details
Main Authors: Dennis L. Foss, Andres H. Gutiérrez, Meggan Bandrick, Sudeep Perumbakkam, Anne S. De Groot, William D. Martin, Frances E. Terry, Alvaro Aldaz, James R.D. Allison, Jose Angulo
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Veterinary Vaccine
Subjects:
PCV2
Vaccine
T cell epitope comparison
EpiCC
Genotype evolution
Online Access:http://www.sciencedirect.com/science/article/pii/S2772535923000161

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