Study of Serum level of Chrome in Bladder Cancer Patients

ABSTRACT Introduction & Objective: Chrome (Cr) is one of the carcinogen trace elements that its role in cancer induction is documented in many studies. In spite o this, there are limited studies about the relationship between chrome and bladder cancer. So we decided to study the serum concentra...

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Main Authors: H Mazdak, Mirkheshti, A Movahedian, F Yazdekhasti, E Behzad, M Shafian, N Ebadati
Format: Article
Language:fas
Published: Yasuj University Of Medical Sciences 2008-12-01
Series:Armaghane Danesh Bimonthly Journal
Subjects:
Online Access:http://armaghanj.yums.ac.ir/browse.php?a_code=A-10-1-392&slc_lang=en&sid=1
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author H Mazdak
Mirkheshti
A Movahedian
F Yazdekhasti
E Behzad
M Shafian
N Ebadati
author_facet H Mazdak
Mirkheshti
A Movahedian
F Yazdekhasti
E Behzad
M Shafian
N Ebadati
author_sort H Mazdak
collection DOAJ
description ABSTRACT Introduction & Objective: Chrome (Cr) is one of the carcinogen trace elements that its role in cancer induction is documented in many studies. In spite o this, there are limited studies about the relationship between chrome and bladder cancer. So we decided to study the serum concentration of Cr in patients with bladder cancer in comparison with healthy individuals. Materials & method: During this case control study, 51 patients with bladder cancer and 58 normal subjects, after matching in age, sex and smoking habits with case group, were selected. Blood samples were collected from each cases. Serum level of Cr was measured in all samples by using the Flameless Atomic Absorption Spectrophotometer. Finally data were analyzed, using student t test. Results: Mean age of participants was 62.74 ± 14.63 years in control group and 58.2 ± 9.8 years in case group. Mean of serum Cr concentration was 128.82 ± 16.99 µg/L in bladder cancer patients and 121.93 ± 16.67 µg/L in control group. The difference in Cr level of serum was significant between two groups (p < 0.05). Conclusion: Results of this study indicated the high level of Cr in the serum of bladder cancer patients. Performing of some strategies in reduction of environmental contaminations, finding the contaminated sources and modifying them, can be useful, for reduction of serum level of Cr, especially in high risk groups.
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spelling doaj.art-c0720826b807411dbcd24518ebd9eb2f2022-12-22T03:52:04ZfasYasuj University Of Medical SciencesArmaghane Danesh Bimonthly Journal1728-65061728-65142008-12-01133124130Study of Serum level of Chrome in Bladder Cancer PatientsH Mazdak0Mirkheshti1A Movahedian2F Yazdekhasti3E Behzad4M Shafian5N Ebadati6 ABSTRACT Introduction & Objective: Chrome (Cr) is one of the carcinogen trace elements that its role in cancer induction is documented in many studies. In spite o this, there are limited studies about the relationship between chrome and bladder cancer. So we decided to study the serum concentration of Cr in patients with bladder cancer in comparison with healthy individuals. Materials & method: During this case control study, 51 patients with bladder cancer and 58 normal subjects, after matching in age, sex and smoking habits with case group, were selected. Blood samples were collected from each cases. Serum level of Cr was measured in all samples by using the Flameless Atomic Absorption Spectrophotometer. Finally data were analyzed, using student t test. Results: Mean age of participants was 62.74 ± 14.63 years in control group and 58.2 ± 9.8 years in case group. Mean of serum Cr concentration was 128.82 ± 16.99 µg/L in bladder cancer patients and 121.93 ± 16.67 µg/L in control group. The difference in Cr level of serum was significant between two groups (p < 0.05). Conclusion: Results of this study indicated the high level of Cr in the serum of bladder cancer patients. Performing of some strategies in reduction of environmental contaminations, finding the contaminated sources and modifying them, can be useful, for reduction of serum level of Cr, especially in high risk groups.http://armaghanj.yums.ac.ir/browse.php?a_code=A-10-1-392&slc_lang=en&sid=1KEYWORDS:Bladder CancerChrometrace element
spellingShingle H Mazdak
Mirkheshti
A Movahedian
F Yazdekhasti
E Behzad
M Shafian
N Ebadati
Study of Serum level of Chrome in Bladder Cancer Patients
Armaghane Danesh Bimonthly Journal
KEYWORDS:Bladder Cancer
Chrome
trace element
title Study of Serum level of Chrome in Bladder Cancer Patients
title_full Study of Serum level of Chrome in Bladder Cancer Patients
title_fullStr Study of Serum level of Chrome in Bladder Cancer Patients
title_full_unstemmed Study of Serum level of Chrome in Bladder Cancer Patients
title_short Study of Serum level of Chrome in Bladder Cancer Patients
title_sort study of serum level of chrome in bladder cancer patients
topic KEYWORDS:Bladder Cancer
Chrome
trace element
url http://armaghanj.yums.ac.ir/browse.php?a_code=A-10-1-392&slc_lang=en&sid=1
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AT amovahedian studyofserumlevelofchromeinbladdercancerpatients
AT fyazdekhasti studyofserumlevelofchromeinbladdercancerpatients
AT ebehzad studyofserumlevelofchromeinbladdercancerpatients
AT mshafian studyofserumlevelofchromeinbladdercancerpatients
AT nebadati studyofserumlevelofchromeinbladdercancerpatients