A review of the reproductive toxicity of environmental contaminants in Caenorhabditis elegans
The release of several environmental pollutants poses a potential threat to the several ecosystems and humans. Reproductive toxicity represents one of the most significant toxic effects of environmental contaminants. It is necessary to assess reproductive toxicity and the mechanisms underlying envir...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2022-09-01
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| Series: | Hygiene and Environmental Health Advances |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2773049222000071 |
| _version_ | 1797753916940615680 |
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| author | Yunjiang Yu Haibo Chen Xin Hua Chen Wang Chenyin Dong Dongli Xie Shihui Tan Mingdeng Xiang Hui Li |
| author_facet | Yunjiang Yu Haibo Chen Xin Hua Chen Wang Chenyin Dong Dongli Xie Shihui Tan Mingdeng Xiang Hui Li |
| author_sort | Yunjiang Yu |
| collection | DOAJ |
| description | The release of several environmental pollutants poses a potential threat to the several ecosystems and humans. Reproductive toxicity represents one of the most significant toxic effects of environmental contaminants. It is necessary to assess reproductive toxicity and the mechanisms underlying environmental toxicity in organisms. Because of its unique features in toxicology research, Caenorhabditis elegans is an important animal model used for the toxicity assessment of environmental contaminants. In this review, we introduce the reproductive toxicity and mechanisms underlying the actions of environmental contaminants, including heavy metals, organic pollutants, particulate matter, microplastics, nanomaterials, and irradiation. Moreover, we have put forth some perspectives about toxicity assessments, transgenerational toxicity, and toxicological mechanisms of environmental contaminants in the future. |
| first_indexed | 2024-03-12T17:24:52Z |
| format | Article |
| id | doaj.art-c0782688f8c24fb6b5bf072b9b20cb71 |
| institution | Directory Open Access Journal |
| issn | 2773-0492 |
| language | English |
| last_indexed | 2024-03-12T17:24:52Z |
| publishDate | 2022-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Hygiene and Environmental Health Advances |
| spelling | doaj.art-c0782688f8c24fb6b5bf072b9b20cb712023-08-05T05:18:17ZengElsevierHygiene and Environmental Health Advances2773-04922022-09-013100007A review of the reproductive toxicity of environmental contaminants in Caenorhabditis elegansYunjiang Yu0Haibo Chen1Xin Hua2Chen Wang3Chenyin Dong4Dongli Xie5Shihui Tan6Mingdeng Xiang7Hui Li8State Environmental Protection Key Laboratory of Environmental Pollution Health Risk Assessment, South China Institute of Environmental Sciences, Ministry of Ecology and Environment, Guangzhou 510655, PR China; Corresponding authors.State Environmental Protection Key Laboratory of Environmental Pollution Health Risk Assessment, South China Institute of Environmental Sciences, Ministry of Ecology and Environment, Guangzhou 510655, PR China; Institute for Environmental pollution and health, School of Environmental and Chemical Engineering, Shanghai University, Shanghai 200444, PR ChinaState Environmental Protection Key Laboratory of Environmental Pollution Health Risk Assessment, South China Institute of Environmental Sciences, Ministry of Ecology and Environment, Guangzhou 510655, PR ChinaInstitute for Environmental pollution and health, School of Environmental and Chemical Engineering, Shanghai University, Shanghai 200444, PR ChinaState Environmental Protection Key Laboratory of Environmental Pollution Health Risk Assessment, South China Institute of Environmental Sciences, Ministry of Ecology and Environment, Guangzhou 510655, PR ChinaState Environmental Protection Key Laboratory of Environmental Pollution Health Risk Assessment, South China Institute of Environmental Sciences, Ministry of Ecology and Environment, Guangzhou 510655, PR China; College of Environmental and Chemical Engineering, Chongqing Three Gorges University, Wanzhou 404100, PR ChinaState Environmental Protection Key Laboratory of Environmental Pollution Health Risk Assessment, South China Institute of Environmental Sciences, Ministry of Ecology and Environment, Guangzhou 510655, PR China; School of Public Health, China Medical University, Liaoning 110122, PR ChinaState Environmental Protection Key Laboratory of Environmental Pollution Health Risk Assessment, South China Institute of Environmental Sciences, Ministry of Ecology and Environment, Guangzhou 510655, PR ChinaInstitute for Environmental pollution and health, School of Environmental and Chemical Engineering, Shanghai University, Shanghai 200444, PR China; Corresponding authors.The release of several environmental pollutants poses a potential threat to the several ecosystems and humans. Reproductive toxicity represents one of the most significant toxic effects of environmental contaminants. It is necessary to assess reproductive toxicity and the mechanisms underlying environmental toxicity in organisms. Because of its unique features in toxicology research, Caenorhabditis elegans is an important animal model used for the toxicity assessment of environmental contaminants. In this review, we introduce the reproductive toxicity and mechanisms underlying the actions of environmental contaminants, including heavy metals, organic pollutants, particulate matter, microplastics, nanomaterials, and irradiation. Moreover, we have put forth some perspectives about toxicity assessments, transgenerational toxicity, and toxicological mechanisms of environmental contaminants in the future.http://www.sciencedirect.com/science/article/pii/S2773049222000071Environmental contaminantsC. elegansReproductive toxicityMechanism |
| spellingShingle | Yunjiang Yu Haibo Chen Xin Hua Chen Wang Chenyin Dong Dongli Xie Shihui Tan Mingdeng Xiang Hui Li A review of the reproductive toxicity of environmental contaminants in Caenorhabditis elegans Hygiene and Environmental Health Advances Environmental contaminants C. elegans Reproductive toxicity Mechanism |
| title | A review of the reproductive toxicity of environmental contaminants in Caenorhabditis elegans |
| title_full | A review of the reproductive toxicity of environmental contaminants in Caenorhabditis elegans |
| title_fullStr | A review of the reproductive toxicity of environmental contaminants in Caenorhabditis elegans |
| title_full_unstemmed | A review of the reproductive toxicity of environmental contaminants in Caenorhabditis elegans |
| title_short | A review of the reproductive toxicity of environmental contaminants in Caenorhabditis elegans |
| title_sort | review of the reproductive toxicity of environmental contaminants in caenorhabditis elegans |
| topic | Environmental contaminants C. elegans Reproductive toxicity Mechanism |
| url | http://www.sciencedirect.com/science/article/pii/S2773049222000071 |
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