Mitochondrial aberrations during the progression of disuse atrophy differentially affect male and female mice

Mitochondrial aberrations during the progression of disuse atrophy differentially affect male and female mice

Abstract Background Disuse decreases muscle size and is predictive of mortality across multiple pathologies. Detriments to mitochondrial function are hypothesized to underlie disuse‐induced muscle atrophy. Little data exist on early mechanisms contributing to onset of these pathologies, nor is it kn...

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Bibliographic Details
Main Authors: Megan E. Rosa‐Caldwell, Seongkyun Lim, Wesley S. Haynie, Jacob L. Brown, David E. Lee, Kirsten R. Dunlap, Lisa T. Jansen, Tyrone A. Washington, Michael P. Wiggs, Nicholas P. Greene
Format: Article
Language:English
Published: Wiley 2021-12-01
Series:Journal of Cachexia, Sarcopenia and Muscle
Subjects:
Sex differences
Muscle
Catabolism
Mitophagy
Autophagy
Online Access:https://doi.org/10.1002/jcsm.12809

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