Ameliorative Potential of Donepezil with or without Prednisolone in Bleomycin-Induced Pulmonary Fibrosis in Rats: Involvement of the Anti-Inflammatory, Antioxidant, and the Antifibrotic Pathways

Ameliorative Potential of Donepezil with or without Prednisolone in Bleomycin-Induced Pulmonary Fibrosis in Rats: Involvement of the Anti-Inflammatory, Antioxidant, and the Antifibrotic Pathways

<i>Background and Objectives:</i> Bleomycin-induced pulmonary fibrosis is one of the serious complications that may limit the use of bleomycin in cancer therapy. To date, there is no effective remedy for the amelioration of this condition. Donepezil, an anti-Alzheimer’s medication, has r...

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Bibliographic Details
Main Authors: Shery Mina, Dina M. Elfeky, Ahmed M. Kabel, Sabeha E. Hedya
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Medicina
Subjects:
pulmonary fibrosis
bleomycin
prednisolone
donepezil
rats
Online Access:https://www.mdpi.com/1648-9144/59/5/980

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