NapB Restores cytochrome c biosynthesis in bacterial dsbD-deficient mutants

The DsbD protein is normally required for cytochrome c maturation (Ccm) in bacteria. With cytochrome c-rich Shewanella oneidensis as the research model, NapB, the small subunit of the nitrate reductase which is a cytochrome c per se, was found to suppress the Ccm defect resulting from DsbD loss unde...

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Main Authors: Kailun Guo, Xue Feng, Weining Sun, Sirui Han, Shihua Wu, Haichun Gao
Format: Article
Language:English
Published: Nature Portfolio 2022-01-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-022-03034-3
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author Kailun Guo
Xue Feng
Weining Sun
Sirui Han
Shihua Wu
Haichun Gao
author_facet Kailun Guo
Xue Feng
Weining Sun
Sirui Han
Shihua Wu
Haichun Gao
author_sort Kailun Guo
collection DOAJ
description The DsbD protein is normally required for cytochrome c maturation (Ccm) in bacteria. With cytochrome c-rich Shewanella oneidensis as the research model, NapB, the small subunit of the nitrate reductase which is a cytochrome c per se, was found to suppress the Ccm defect resulting from DsbD loss under anaerobic conditions.
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issn 2399-3642
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spelling doaj.art-c07f690578454496bb690a8cbe3e97922022-12-22T04:15:27ZengNature PortfolioCommunications Biology2399-36422022-01-015111210.1038/s42003-022-03034-3NapB Restores cytochrome c biosynthesis in bacterial dsbD-deficient mutantsKailun Guo0Xue Feng1Weining Sun2Sirui Han3Shihua Wu4Haichun Gao5Institute of Microbiology and College of Life Sciences, Zhejiang UniversityInstitute of Microbiology and College of Life Sciences, Zhejiang UniversityInstitute of Microbiology and College of Life Sciences, Zhejiang UniversityInstitute of Microbiology and College of Life Sciences, Zhejiang UniversityInstitute of Microbiology and College of Life Sciences, Zhejiang UniversityInstitute of Microbiology and College of Life Sciences, Zhejiang UniversityThe DsbD protein is normally required for cytochrome c maturation (Ccm) in bacteria. With cytochrome c-rich Shewanella oneidensis as the research model, NapB, the small subunit of the nitrate reductase which is a cytochrome c per se, was found to suppress the Ccm defect resulting from DsbD loss under anaerobic conditions.https://doi.org/10.1038/s42003-022-03034-3
spellingShingle Kailun Guo
Xue Feng
Weining Sun
Sirui Han
Shihua Wu
Haichun Gao
NapB Restores cytochrome c biosynthesis in bacterial dsbD-deficient mutants
Communications Biology
title NapB Restores cytochrome c biosynthesis in bacterial dsbD-deficient mutants
title_full NapB Restores cytochrome c biosynthesis in bacterial dsbD-deficient mutants
title_fullStr NapB Restores cytochrome c biosynthesis in bacterial dsbD-deficient mutants
title_full_unstemmed NapB Restores cytochrome c biosynthesis in bacterial dsbD-deficient mutants
title_short NapB Restores cytochrome c biosynthesis in bacterial dsbD-deficient mutants
title_sort napb restores cytochrome c biosynthesis in bacterial dsbd deficient mutants
url https://doi.org/10.1038/s42003-022-03034-3
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AT xuefeng napbrestorescytochromecbiosynthesisinbacterialdsbddeficientmutants
AT weiningsun napbrestorescytochromecbiosynthesisinbacterialdsbddeficientmutants
AT siruihan napbrestorescytochromecbiosynthesisinbacterialdsbddeficientmutants
AT shihuawu napbrestorescytochromecbiosynthesisinbacterialdsbddeficientmutants
AT haichungao napbrestorescytochromecbiosynthesisinbacterialdsbddeficientmutants