Value of osteoprotegerin, RANKL, interleukin-17 in mechanisms of bone metabolism disorders
The relationship between osteoprotegerin, RANKL and interleukin-17 inthe mechanisms of abnormal remodeling of bone tissue during experimental periodontitis was studied in this work. Increased levels of RANKL and pro-inflammatory IL-17 were found, as well as a decrease in the serum osteoprotegerin co...
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| Format: | Article |
| Language: | English |
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Kazimierz Wielki University
2017-07-01
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| Series: | Journal of Education, Health and Sport |
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| Online Access: | http://www.ojs.ukw.edu.pl/index.php/johs/article/view/5254 |
| _version_ | 1819091553308639232 |
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| author | V. F. Cheremisina |
| author_facet | V. F. Cheremisina |
| author_sort | V. F. Cheremisina |
| collection | DOAJ |
| description | The relationship between osteoprotegerin, RANKL and interleukin-17 inthe mechanisms of abnormal remodeling of bone tissue during experimental periodontitis was studied in this work. Increased levels of RANKL and pro-inflammatory IL-17 were found, as well as a decrease in the serum osteoprotegerin content of rat experimental rats. The revealed correlations between the level of interleukin-17, RANKL and osteoprotegerin indicate an important role of the studied cytokines in bone remodeling disorders during periodontitis. |
| first_indexed | 2024-12-21T22:41:33Z |
| format | Article |
| id | doaj.art-c08025cf5fd34912ae6c27ae54389238 |
| institution | Directory Open Access Journal |
| issn | 2391-8306 |
| language | English |
| last_indexed | 2024-12-21T22:41:33Z |
| publishDate | 2017-07-01 |
| publisher | Kazimierz Wielki University |
| record_format | Article |
| series | Journal of Education, Health and Sport |
| spelling | doaj.art-c08025cf5fd34912ae6c27ae543892382022-12-21T18:47:49ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062017-07-01771257126410.5281/zenodo.11654194894Value of osteoprotegerin, RANKL, interleukin-17 in mechanisms of bone metabolism disordersV. F. Cheremisina0National University of PharmacyThe relationship between osteoprotegerin, RANKL and interleukin-17 inthe mechanisms of abnormal remodeling of bone tissue during experimental periodontitis was studied in this work. Increased levels of RANKL and pro-inflammatory IL-17 were found, as well as a decrease in the serum osteoprotegerin content of rat experimental rats. The revealed correlations between the level of interleukin-17, RANKL and osteoprotegerin indicate an important role of the studied cytokines in bone remodeling disorders during periodontitis.http://www.ojs.ukw.edu.pl/index.php/johs/article/view/5254cytokines, remodeling of bone tissue, periodontitis |
| spellingShingle | V. F. Cheremisina Value of osteoprotegerin, RANKL, interleukin-17 in mechanisms of bone metabolism disorders Journal of Education, Health and Sport cytokines, remodeling of bone tissue, periodontitis |
| title | Value of osteoprotegerin, RANKL, interleukin-17 in mechanisms of bone metabolism disorders |
| title_full | Value of osteoprotegerin, RANKL, interleukin-17 in mechanisms of bone metabolism disorders |
| title_fullStr | Value of osteoprotegerin, RANKL, interleukin-17 in mechanisms of bone metabolism disorders |
| title_full_unstemmed | Value of osteoprotegerin, RANKL, interleukin-17 in mechanisms of bone metabolism disorders |
| title_short | Value of osteoprotegerin, RANKL, interleukin-17 in mechanisms of bone metabolism disorders |
| title_sort | value of osteoprotegerin rankl interleukin 17 in mechanisms of bone metabolism disorders |
| topic | cytokines, remodeling of bone tissue, periodontitis |
| url | http://www.ojs.ukw.edu.pl/index.php/johs/article/view/5254 |
| work_keys_str_mv | AT vfcheremisina valueofosteoprotegerinranklinterleukin17inmechanismsofbonemetabolismdisorders |