Plant-based vaccines against respiratory diseases: current status and future prospects

Introduction: Respiratory infections have an enormous, worldwide epidemiologic impact on humans and animals. Among the prophylactic measures, vaccination has the potential to neutralize this impact. New technologies for vaccine production and delivery are of importance in this field since they offer...

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Main Authors: Verónica A. Márquez-Escobar, Sergio Rosales-Mendoza, Josué I. Beltrán-López, Omar González-Ortega
Format: Article
Language:English
Published: Taylor & Francis Group 2017-02-01
Series:Expert Review of Vaccines
Subjects:
Online Access:http://dx.doi.org/10.1080/14760584.2017.1232167
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author Verónica A. Márquez-Escobar
Sergio Rosales-Mendoza
Josué I. Beltrán-López
Omar González-Ortega
author_facet Verónica A. Márquez-Escobar
Sergio Rosales-Mendoza
Josué I. Beltrán-López
Omar González-Ortega
author_sort Verónica A. Márquez-Escobar
collection DOAJ
description Introduction: Respiratory infections have an enormous, worldwide epidemiologic impact on humans and animals. Among the prophylactic measures, vaccination has the potential to neutralize this impact. New technologies for vaccine production and delivery are of importance in this field since they offer the potential to develop new immunization approaches overriding the current limitations that comprise high cost, safety issues, and limited efficacy. Areas covered: In the present review, the state of the art in developing plant-based vaccines against respiratory diseases is presented. The review was based on the analysis of current biomedical literature. Expert commentary: Preclinical and clinical evaluations of several vaccine candidates against influenza, tuberculosis, respiratory syncytial virus, pneumonia, anthrax and asthma are discussed and placed in perspective.
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spelling doaj.art-c08759289e4f414c9d753c57a8d0f2912023-09-20T10:18:01ZengTaylor & Francis GroupExpert Review of Vaccines1476-05841744-83952017-02-0116213714910.1080/14760584.2017.12321671232167Plant-based vaccines against respiratory diseases: current status and future prospectsVerónica A. Márquez-Escobar0Sergio Rosales-Mendoza1Josué I. Beltrán-López2Omar González-Ortega3Universidad Autonoma de San Luis PotosiUniversidad Autonoma de San Luis PotosiUniversidad Autonoma de San Luis PotosiUniversidad Autonoma de San Luis PotosiIntroduction: Respiratory infections have an enormous, worldwide epidemiologic impact on humans and animals. Among the prophylactic measures, vaccination has the potential to neutralize this impact. New technologies for vaccine production and delivery are of importance in this field since they offer the potential to develop new immunization approaches overriding the current limitations that comprise high cost, safety issues, and limited efficacy. Areas covered: In the present review, the state of the art in developing plant-based vaccines against respiratory diseases is presented. The review was based on the analysis of current biomedical literature. Expert commentary: Preclinical and clinical evaluations of several vaccine candidates against influenza, tuberculosis, respiratory syncytial virus, pneumonia, anthrax and asthma are discussed and placed in perspective.http://dx.doi.org/10.1080/14760584.2017.1232167bronchus associated lymphoid tissuecellular immunityoral immunizationsubunit vaccineparenteral immunizationmolecular pharming
spellingShingle Verónica A. Márquez-Escobar
Sergio Rosales-Mendoza
Josué I. Beltrán-López
Omar González-Ortega
Plant-based vaccines against respiratory diseases: current status and future prospects
Expert Review of Vaccines
bronchus associated lymphoid tissue
cellular immunity
oral immunization
subunit vaccine
parenteral immunization
molecular pharming
title Plant-based vaccines against respiratory diseases: current status and future prospects
title_full Plant-based vaccines against respiratory diseases: current status and future prospects
title_fullStr Plant-based vaccines against respiratory diseases: current status and future prospects
title_full_unstemmed Plant-based vaccines against respiratory diseases: current status and future prospects
title_short Plant-based vaccines against respiratory diseases: current status and future prospects
title_sort plant based vaccines against respiratory diseases current status and future prospects
topic bronchus associated lymphoid tissue
cellular immunity
oral immunization
subunit vaccine
parenteral immunization
molecular pharming
url http://dx.doi.org/10.1080/14760584.2017.1232167
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