A Comparative Study of Pulmonary Functions in Patients with Type 2 Diabetes Mellitus and Normal Individuals
Background: Diabetes mellitus is a multi-system disorder that affects many organs of the bodyincluding the lung. Thus, the lung is considered a 'target organ' in diabetes mellitus. Thepresent study is undertaken to evaluate the impact of type 2 diabetes mellitus onpulmonary functions o...
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| Format: | Article |
| Language: | English |
| Published: |
Prathima Institute of Medical Sciences
2021-07-01
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| Series: | Perspectives In Medical Research |
| Subjects: | |
| Online Access: | https://www.pimr.org.in/2021-vol9-issue-1/originalarticle10_v1.pdf |
| Summary: | Background: Diabetes mellitus is a multi-system disorder that
affects many organs of the bodyincluding the lung. Thus, the
lung is considered a 'target organ' in diabetes mellitus.
Thepresent study is undertaken to evaluate the impact of type
2 diabetes mellitus onpulmonary functions of adult male
diabetic patients and to compare between type 2diabetes
mellitus patients and healthy adult male subjects.
Methods: Hundred adult male type 2 diabetic patients were
selected from the diabetic clinic,
Prathima Institute of Medical Sciences, Nagunur, Karimnagar,
and 100 adult male healthy subjects were selected randomly
among the general population from Karimnagar city.
spirograms were recorded by Spirowin PC-basedSpirometer.
Parameters such as Forced Vital Capacity (FVC), Forced
ExpiratoryVolume in 1st second (FEV1), the ratio of FEV1/FVC,
Forced Expiratory Flow (FEF) inthe Middle Half of FVC, and
Peak Expiratory Rate (PEFR) were assessed and analyzedby
using the paired t-test and ANOVA.
Results: Diabetes mellitus has a negative impact on pulmonary
functions when compared with healthy subjects. In this study
type 2 diabetes mellitus patients showed a significantly greater
percentage decline in FVC, FEV1, FEF25-75%, PEFR, and a slight
increase in the ratio of FEV1/FVC suggestive of the restrictive
pulmonary disorder.
Conclusion:
This study found the pulmonary functions FVC, FEV1,
FEF25%-75%, and PEFR are decreased inType 2 diabetes
mellitus compared to controls. FEV1/FVC% slightly increased
in Type 2 diabetes mellitus, which is indicative of the restrictive
pulmonary disorder. |
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| ISSN: | 2348-1447 2348-229X |