The Relations Between Anti-Toxoplasma IgG and IgM Antibodies With Avidity Index
Objective: Toxoplasma gondii is one of the obligatory intracellular protozoan parasite with worldwide distribution. Diagnosis of acute infection is of importance in pregnancy due to congenital infection and its sequels. One of the tools for distinguishing acute from chronic infection is avidity ELIS...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Aras Part Medical International Press
2017-10-01
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| Series: | Crescent Journal of Medical and Biological Sciences |
| Subjects: | |
| Online Access: | http://cjmb.org/uploads/pdf/pdf_CJMB_66.pdf |
| _version_ | 1818351769930956800 |
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| author | Saeedeh Shojaee Amir Hossien Rahbari Hossien Keshavarz |
| author_facet | Saeedeh Shojaee Amir Hossien Rahbari Hossien Keshavarz |
| author_sort | Saeedeh Shojaee |
| collection | DOAJ |
| description | Objective: Toxoplasma gondii is one of the obligatory intracellular protozoan parasite with worldwide distribution. Diagnosis of acute infection is of importance in pregnancy due to congenital infection and its sequels. One of the tools for distinguishing acute from chronic infection is avidity ELISA method. This study was performed to evaluate the correlation between IgG and IgM antibodies and the of avidity index (AI).
Materials and Methods: A total of 100 serum samples were collected from different laboratories, with detectable anti-T. gondii IgG and IgM antibodies. Avidity IgG ELISA method was performed and AI was calculated.
Results:In the present study no relation between IgG concentration and the mean of AI was observed. The relation between the means of AI and concentrations of IgM antibody in 98% of acute sera was reverse.
Conclusion: Irrespective to titers of IgG and IgM antibodies, IgG avidity ELISA test could distinguish acute from chronic phase of T. gondii infection. |
| first_indexed | 2024-12-13T18:43:01Z |
| format | Article |
| id | doaj.art-c08d21a1b6b9468cbc7caa82840cd495 |
| institution | Directory Open Access Journal |
| issn | 2148-9696 2148-9696 |
| language | English |
| last_indexed | 2024-12-13T18:43:01Z |
| publishDate | 2017-10-01 |
| publisher | Aras Part Medical International Press |
| record_format | Article |
| series | Crescent Journal of Medical and Biological Sciences |
| spelling | doaj.art-c08d21a1b6b9468cbc7caa82840cd4952022-12-21T23:35:09ZengAras Part Medical International PressCrescent Journal of Medical and Biological Sciences2148-96962148-96962017-10-0144177179The Relations Between Anti-Toxoplasma IgG and IgM Antibodies With Avidity IndexSaeedeh Shojaee0 Amir Hossien Rahbari1Hossien Keshavarz2Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, IranDepartment of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, IranDepartment of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, IranObjective: Toxoplasma gondii is one of the obligatory intracellular protozoan parasite with worldwide distribution. Diagnosis of acute infection is of importance in pregnancy due to congenital infection and its sequels. One of the tools for distinguishing acute from chronic infection is avidity ELISA method. This study was performed to evaluate the correlation between IgG and IgM antibodies and the of avidity index (AI). Materials and Methods: A total of 100 serum samples were collected from different laboratories, with detectable anti-T. gondii IgG and IgM antibodies. Avidity IgG ELISA method was performed and AI was calculated. Results:In the present study no relation between IgG concentration and the mean of AI was observed. The relation between the means of AI and concentrations of IgM antibody in 98% of acute sera was reverse. Conclusion: Irrespective to titers of IgG and IgM antibodies, IgG avidity ELISA test could distinguish acute from chronic phase of T. gondii infection.http://cjmb.org/uploads/pdf/pdf_CJMB_66.pdfToxoplasma gondiiIgGIgMAvidity |
| spellingShingle | Saeedeh Shojaee Amir Hossien Rahbari Hossien Keshavarz The Relations Between Anti-Toxoplasma IgG and IgM Antibodies With Avidity Index Crescent Journal of Medical and Biological Sciences Toxoplasma gondii IgG IgM Avidity |
| title | The Relations Between Anti-Toxoplasma IgG and IgM Antibodies With Avidity Index |
| title_full | The Relations Between Anti-Toxoplasma IgG and IgM Antibodies With Avidity Index |
| title_fullStr | The Relations Between Anti-Toxoplasma IgG and IgM Antibodies With Avidity Index |
| title_full_unstemmed | The Relations Between Anti-Toxoplasma IgG and IgM Antibodies With Avidity Index |
| title_short | The Relations Between Anti-Toxoplasma IgG and IgM Antibodies With Avidity Index |
| title_sort | relations between anti toxoplasma igg and igm antibodies with avidity index |
| topic | Toxoplasma gondii IgG IgM Avidity |
| url | http://cjmb.org/uploads/pdf/pdf_CJMB_66.pdf |
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