Photodynamic Therapy in Ocular Oncology

Although introduced for the treatment of maculopathies, photodynamic therapy (PDT) is now largely used in some eye cancers treatment. The selective tissue damage with PDT is achieved by sequestration of the photosensitizer in the target tissue and focal activation of the photosensitizer by low energ...

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Main Authors: Maria Antonietta Blasi, Monica Maria Pagliara, Angela Lanza, Maria Grazia Sammarco, Carmela Grazia Caputo, Gabriela Grimaldi, Andrea Scupola
Format: Article
Language:English
Published: MDPI AG 2018-02-01
Series:Biomedicines
Subjects:
Online Access:http://www.mdpi.com/2227-9059/6/1/17
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author Maria Antonietta Blasi
Monica Maria Pagliara
Angela Lanza
Maria Grazia Sammarco
Carmela Grazia Caputo
Gabriela Grimaldi
Andrea Scupola
author_facet Maria Antonietta Blasi
Monica Maria Pagliara
Angela Lanza
Maria Grazia Sammarco
Carmela Grazia Caputo
Gabriela Grimaldi
Andrea Scupola
author_sort Maria Antonietta Blasi
collection DOAJ
description Although introduced for the treatment of maculopathies, photodynamic therapy (PDT) is now largely used in some eye cancers treatment. The selective tissue damage with PDT is achieved by sequestration of the photosensitizer in the target tissue and focal activation of the photosensitizer by low energy directed light. In this way, it is possible to achieve the destruction of the tumor tissue by safeguarding the surrounding healthy structures. Our study describes the clinical uses and efficacy of photodynamic therapy in ocular oncology.
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spelling doaj.art-c08d59f6a1f141be845a43dace1439802022-12-21T20:32:00ZengMDPI AGBiomedicines2227-90592018-02-01611710.3390/biomedicines6010017biomedicines6010017Photodynamic Therapy in Ocular OncologyMaria Antonietta Blasi0Monica Maria Pagliara1Angela Lanza2Maria Grazia Sammarco3Carmela Grazia Caputo4Gabriela Grimaldi5Andrea Scupola6Department of Ophthalmology, Catholic University, 00168 Rome, ItalyDepartment of Ophthalmology, Catholic University, 00168 Rome, ItalyDepartment of Ophthalmology, Catholic University, 00168 Rome, ItalyDepartment of Ophthalmology, Catholic University, 00168 Rome, ItalyDepartment of Ophthalmology, Catholic University, 00168 Rome, ItalyDepartment of Ophthalmology, Catholic University, 00168 Rome, ItalyDepartment of Ophthalmology, Catholic University, 00168 Rome, ItalyAlthough introduced for the treatment of maculopathies, photodynamic therapy (PDT) is now largely used in some eye cancers treatment. The selective tissue damage with PDT is achieved by sequestration of the photosensitizer in the target tissue and focal activation of the photosensitizer by low energy directed light. In this way, it is possible to achieve the destruction of the tumor tissue by safeguarding the surrounding healthy structures. Our study describes the clinical uses and efficacy of photodynamic therapy in ocular oncology.http://www.mdpi.com/2227-9059/6/1/17photodynamic therapy (PDT)PDTocular tumorsuveal melanomachoroidal hemangiomauveal metastasesvasoproliferative tumors
spellingShingle Maria Antonietta Blasi
Monica Maria Pagliara
Angela Lanza
Maria Grazia Sammarco
Carmela Grazia Caputo
Gabriela Grimaldi
Andrea Scupola
Photodynamic Therapy in Ocular Oncology
Biomedicines
photodynamic therapy (PDT)
PDT
ocular tumors
uveal melanoma
choroidal hemangioma
uveal metastases
vasoproliferative tumors
title Photodynamic Therapy in Ocular Oncology
title_full Photodynamic Therapy in Ocular Oncology
title_fullStr Photodynamic Therapy in Ocular Oncology
title_full_unstemmed Photodynamic Therapy in Ocular Oncology
title_short Photodynamic Therapy in Ocular Oncology
title_sort photodynamic therapy in ocular oncology
topic photodynamic therapy (PDT)
PDT
ocular tumors
uveal melanoma
choroidal hemangioma
uveal metastases
vasoproliferative tumors
url http://www.mdpi.com/2227-9059/6/1/17
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AT monicamariapagliara photodynamictherapyinocularoncology
AT angelalanza photodynamictherapyinocularoncology
AT mariagraziasammarco photodynamictherapyinocularoncology
AT carmelagraziacaputo photodynamictherapyinocularoncology
AT gabrielagrimaldi photodynamictherapyinocularoncology
AT andreascupola photodynamictherapyinocularoncology