Pneumothorax in an early phase after allogeneic hematopoietic stem cell transplantation

Pneumothorax is very rare after early phase of hematopoietic stem cell transplantation (HSCT) and usually accompanied with pulmonary chronic graft-<em>versus</em>-host disease (GVHD), such as bronchiolitis obliterans and bronchiolitis obliterans organizing pneumonia. The present study de...

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Main Authors: Yasuhiro Ebihara, Shohei Yamamoto, Shinji Mochizuki, Masao Tsukada, Yuki Taya, Toshiro Kawakita, Seiko Kato, Jun Ooi, Satoshi Takahashi, Arinobu Tojo, Kohichiro Tsuji
Format: Article
Language:English
Published: MDPI AG 2013-06-01
Series:Hematology Reports
Subjects:
Online Access:http://www.pagepress.org/journals/index.php/hr/article/view/4801
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author Yasuhiro Ebihara
Shohei Yamamoto
Shinji Mochizuki
Masao Tsukada
Yuki Taya
Toshiro Kawakita
Seiko Kato
Jun Ooi
Satoshi Takahashi
Arinobu Tojo
Kohichiro Tsuji
author_facet Yasuhiro Ebihara
Shohei Yamamoto
Shinji Mochizuki
Masao Tsukada
Yuki Taya
Toshiro Kawakita
Seiko Kato
Jun Ooi
Satoshi Takahashi
Arinobu Tojo
Kohichiro Tsuji
author_sort Yasuhiro Ebihara
collection DOAJ
description Pneumothorax is very rare after early phase of hematopoietic stem cell transplantation (HSCT) and usually accompanied with pulmonary chronic graft-<em>versus</em>-host disease (GVHD), such as bronchiolitis obliterans and bronchiolitis obliterans organizing pneumonia. The present study describes the case of a seventeen-year-old male diagnosed with acute myeloid leukemia who underwent allogeneic bone marrow transplantation (BMT). Pneumothorax occurred at day 43 after BMT. Pneumothorax occurred in early phase of HSCT is extremely rare. The early onset of acute GVHD and the entity of cytomegalovirus might worsen the pulmonary tissue damages for the onset of pneumothorax, indicating that we should be aware of the possibility to occur pneumothorax even in the early period after allogeneic HSCT.
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spelling doaj.art-c08e6e27b5c646acb11241536260c0c52023-02-02T06:39:43ZengMDPI AGHematology Reports2038-83222038-83302013-06-0152e10e1010.4081/hr.2013.e102546Pneumothorax in an early phase after allogeneic hematopoietic stem cell transplantationYasuhiro Ebihara0Shohei Yamamoto1Shinji Mochizuki2Masao Tsukada3Yuki Taya4Toshiro Kawakita5Seiko Kato6Jun Ooi7Satoshi Takahashi8Arinobu Tojo9Kohichiro Tsuji10Department of Pediatric Hematology/Oncology, Research Hospital, The Institute of Medical Science, The University of TokyoDepartment of Pediatric Hematology/Oncology, Research Hospital, The Institute of Medical Science, The University of TokyoDivision of Stem Cell Processing, Center for Stem Cell Biology and Regenerative Medicine, The Institute of Medical Science, The University of TokyoDepartment of Hematology/Oncology, Research Hospital, The Institute of Medical Science, The University of TokyoDepartment of Hematology/Oncology, Research Hospital, The Institute of Medical Science, The University of TokyoDepartment of Hematology/Oncology, Research Hospital, The Institute of Medical Science, The University of TokyoDepartment of Hematology/Oncology, Research Hospital, The Institute of Medical Science, The University of TokyoDepartment of Hematology/Oncology, Research Hospital, The Institute of Medical Science, The University of TokyoDepartment of Hematology/Oncology, Research Hospital, The Institute of Medical Science, The University of TokyoDepartment of Hematology/Oncology, Research Hospital, The Institute of Medical Science, The University of TokyoDepartment of Pediatric Hematology/Oncology, Research Hospital, The Institute of Medical Science, The University of Tokyo; Division of Stem Cell Processing, Center for Stem Cell Biology and Regenerative Medicine, The Institute of Medical Science, The University of Tokyo; Department of Pediatrics, Shinshu Ueda Medical CenterPneumothorax is very rare after early phase of hematopoietic stem cell transplantation (HSCT) and usually accompanied with pulmonary chronic graft-<em>versus</em>-host disease (GVHD), such as bronchiolitis obliterans and bronchiolitis obliterans organizing pneumonia. The present study describes the case of a seventeen-year-old male diagnosed with acute myeloid leukemia who underwent allogeneic bone marrow transplantation (BMT). Pneumothorax occurred at day 43 after BMT. Pneumothorax occurred in early phase of HSCT is extremely rare. The early onset of acute GVHD and the entity of cytomegalovirus might worsen the pulmonary tissue damages for the onset of pneumothorax, indicating that we should be aware of the possibility to occur pneumothorax even in the early period after allogeneic HSCT.http://www.pagepress.org/journals/index.php/hr/article/view/4801pneumothorax, air-leak syndrome, allogeneic hematopoietic stem cell transplantation
spellingShingle Yasuhiro Ebihara
Shohei Yamamoto
Shinji Mochizuki
Masao Tsukada
Yuki Taya
Toshiro Kawakita
Seiko Kato
Jun Ooi
Satoshi Takahashi
Arinobu Tojo
Kohichiro Tsuji
Pneumothorax in an early phase after allogeneic hematopoietic stem cell transplantation
Hematology Reports
pneumothorax, air-leak syndrome, allogeneic hematopoietic stem cell transplantation
title Pneumothorax in an early phase after allogeneic hematopoietic stem cell transplantation
title_full Pneumothorax in an early phase after allogeneic hematopoietic stem cell transplantation
title_fullStr Pneumothorax in an early phase after allogeneic hematopoietic stem cell transplantation
title_full_unstemmed Pneumothorax in an early phase after allogeneic hematopoietic stem cell transplantation
title_short Pneumothorax in an early phase after allogeneic hematopoietic stem cell transplantation
title_sort pneumothorax in an early phase after allogeneic hematopoietic stem cell transplantation
topic pneumothorax, air-leak syndrome, allogeneic hematopoietic stem cell transplantation
url http://www.pagepress.org/journals/index.php/hr/article/view/4801
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