Testing for non-inferior mortality: a systematic review of non-inferiority margin sizes and trial characteristics

Testing for non-inferior mortality: a systematic review of non-inferiority margin sizes and trial characteristics

Objective To describe the size and variability of non-inferiority margins used in non-inferiority trials of medications with primary outcomes involving mortality, and to examine the association between trial characteristics and non-inferiority margin size.Design Systematic review.Data sources Medlin...

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Bibliografische gegevens
Hoofdauteurs: Nick Daneman, Robert A Fowler, Sandra Pong, Martin Urner, Nicholas Mitsakakis, Winnie Seto, James S Hutchison, Michelle Science
Formaat: Artikel
Taal:English
Gepubliceerd in: BMJ Publishing Group 2021-04-01
Reeks:BMJ Open
Online toegang:https://bmjopen.bmj.com/content/11/4/e044480.full

Internet

https://bmjopen.bmj.com/content/11/4/e044480.full

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