The Oxidative Stress Markers of Horses—the Comparison with Other Animals and the Influence of Exercise and Disease
Diacron-reactive oxygen metabolite (d-ROM) and biological antioxidant potential (BAP) levels in the serum of horses were measured (ponies, <i>n</i> = 15; thoroughbred, <i>n</i> = 31; other full-sized horses, <i>n</i> = 7). The mean d-ROM levels in horses were sign...
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MDPI AG
2020-04-01
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| Online Access: | https://www.mdpi.com/2076-2615/10/4/617 |
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| author | Saori Shono Azusa Gin Fumiko Minowa Kimihiro Okubo Mariko Mochizuki |
| author_facet | Saori Shono Azusa Gin Fumiko Minowa Kimihiro Okubo Mariko Mochizuki |
| author_sort | Saori Shono |
| collection | DOAJ |
| description | Diacron-reactive oxygen metabolite (d-ROM) and biological antioxidant potential (BAP) levels in the serum of horses were measured (ponies, <i>n</i> = 15; thoroughbred, <i>n</i> = 31; other full-sized horses, <i>n</i> = 7). The mean d-ROM levels in horses were significantly higher (<i>p</i> < 0.001) than those in dairy cattle (<i>n</i> = 25) and dogs (<i>n</i> = 31). However, d-ROM levels in horses were lower than the standard levels reported in humans. When d-ROM and BAP levels were plotted graphically, the points for horses with a disease (ringbone in 1 Japanese sports horse, cellulitis in 1 thoroughbred, melanoma in 1 Lipizzaner) fell outside the group of points for other (non-diseased) horses. A similar separation was seen (using data from other authors) for a horse with <i>Rhodococcus equi</i>, a horse following castration surgery, and a mare following delivery. These results, comparing horses, other animals, and humans, are interesting from the standpoint of comparative medicine, and they contribute to the sparse literature available on d-ROM and BAP levels in animals. Because the level of d-ROM and BAP levels were changed depending on the situation of health, those indexes are promising as indices of health in horses. |
| first_indexed | 2024-03-10T20:42:20Z |
| format | Article |
| id | doaj.art-c090f12e8f1d476fa9a807ff87df6a1a |
| institution | Directory Open Access Journal |
| issn | 2076-2615 |
| language | English |
| last_indexed | 2024-03-10T20:42:20Z |
| publishDate | 2020-04-01 |
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| series | Animals |
| spelling | doaj.art-c090f12e8f1d476fa9a807ff87df6a1a2023-11-19T20:36:24ZengMDPI AGAnimals2076-26152020-04-0110461710.3390/ani10040617The Oxidative Stress Markers of Horses—the Comparison with Other Animals and the Influence of Exercise and DiseaseSaori Shono0Azusa Gin1Fumiko Minowa2Kimihiro Okubo3Mariko Mochizuki4Department of Applied Science, School of Veterinary Nursing and Technology, Nippon Veterinary and Life Science University, Tokyo 180-8602, JapanDepartment of Applied Science, School of Veterinary Nursing and Technology, Nippon Veterinary and Life Science University, Tokyo 180-8602, JapanMinowa Horse Clinic, Tokyo 144-0033, JapanDepartment of Otolaryngology, Graduate School of Medicine, Nippon Medical School, Tokyo 113-8602, JapanDepartment of Applied Science, School of Veterinary Nursing and Technology, Nippon Veterinary and Life Science University, Tokyo 180-8602, JapanDiacron-reactive oxygen metabolite (d-ROM) and biological antioxidant potential (BAP) levels in the serum of horses were measured (ponies, <i>n</i> = 15; thoroughbred, <i>n</i> = 31; other full-sized horses, <i>n</i> = 7). The mean d-ROM levels in horses were significantly higher (<i>p</i> < 0.001) than those in dairy cattle (<i>n</i> = 25) and dogs (<i>n</i> = 31). However, d-ROM levels in horses were lower than the standard levels reported in humans. When d-ROM and BAP levels were plotted graphically, the points for horses with a disease (ringbone in 1 Japanese sports horse, cellulitis in 1 thoroughbred, melanoma in 1 Lipizzaner) fell outside the group of points for other (non-diseased) horses. A similar separation was seen (using data from other authors) for a horse with <i>Rhodococcus equi</i>, a horse following castration surgery, and a mare following delivery. These results, comparing horses, other animals, and humans, are interesting from the standpoint of comparative medicine, and they contribute to the sparse literature available on d-ROM and BAP levels in animals. Because the level of d-ROM and BAP levels were changed depending on the situation of health, those indexes are promising as indices of health in horses.https://www.mdpi.com/2076-2615/10/4/617diacron-reactive oxygen metabolitebiological antioxidant potentialhorseoxidative stress index |
| spellingShingle | Saori Shono Azusa Gin Fumiko Minowa Kimihiro Okubo Mariko Mochizuki The Oxidative Stress Markers of Horses—the Comparison with Other Animals and the Influence of Exercise and Disease Animals diacron-reactive oxygen metabolite biological antioxidant potential horse oxidative stress index |
| title | The Oxidative Stress Markers of Horses—the Comparison with Other Animals and the Influence of Exercise and Disease |
| title_full | The Oxidative Stress Markers of Horses—the Comparison with Other Animals and the Influence of Exercise and Disease |
| title_fullStr | The Oxidative Stress Markers of Horses—the Comparison with Other Animals and the Influence of Exercise and Disease |
| title_full_unstemmed | The Oxidative Stress Markers of Horses—the Comparison with Other Animals and the Influence of Exercise and Disease |
| title_short | The Oxidative Stress Markers of Horses—the Comparison with Other Animals and the Influence of Exercise and Disease |
| title_sort | oxidative stress markers of horses the comparison with other animals and the influence of exercise and disease |
| topic | diacron-reactive oxygen metabolite biological antioxidant potential horse oxidative stress index |
| url | https://www.mdpi.com/2076-2615/10/4/617 |
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