In Vivo Evaluation of ECP Peptide Analogues for the Treatment of <i>Acinetobacter baumannii</i> Infection

In Vivo Evaluation of ECP Peptide Analogues for the Treatment of <i>Acinetobacter baumannii</i> Infection

Antimicrobial peptides (AMPs) are alternative therapeutics to traditional antibiotics against bacterial resistance. Our previous work identified an antimicrobial region at the N-terminus of the eosinophil cationic protein (ECP). Following structure-based analysis, a 30mer peptide (ECPep-L) was desig...

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Bibliographic Details
Main Authors: Jiarui Li, Guillem Prats-Ejarque, Marc Torrent, David Andreu, Klaus Brandenburg, Pablo Fernández-Millán, Ester Boix
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Biomedicines
Subjects:
ECP
AMPs
infection
murine model
Gram-negative bacteria
LPS
Online Access:https://www.mdpi.com/2227-9059/10/2/386

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https://www.mdpi.com/2227-9059/10/2/386

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