In Vivo Evaluation of ECP Peptide Analogues for the Treatment of <i>Acinetobacter baumannii</i> Infection

In Vivo Evaluation of ECP Peptide Analogues for the Treatment of <i>Acinetobacter baumannii</i> Infection

Antimicrobial peptides (AMPs) are alternative therapeutics to traditional antibiotics against bacterial resistance. Our previous work identified an antimicrobial region at the N-terminus of the eosinophil cationic protein (ECP). Following structure-based analysis, a 30mer peptide (ECPep-L) was desig...

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Bibliographic Details
Main Authors:	Jiarui Li, Guillem Prats-Ejarque, Marc Torrent, David Andreu, Klaus Brandenburg, Pablo Fernández-Millán, Ester Boix
Format:	Article
Language:	English
Published:	MDPI AG 2022-02-01
Series:	Biomedicines
Subjects:	ECP AMPs infection murine model Gram-negative bacteria LPS
Online Access:	https://www.mdpi.com/2227-9059/10/2/386

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