Preparation and evaluation of combined inactivated vaccine containing rota, corona viruses, Escherichia coli bacterin and Clostridium perfringens type Ctoxoid (Entero-4)
A conclusive study was conducted for preparation and evaluation of combined inactivated entero-4 vaccine containing bovine rotavirus (BRV), bovine coronavirus (BCV), E. coli K99 and toxoid of C. perfringens type "C". Laboratory and field evaluations were conducted on laboratory animals,...
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| Format: | Article |
| Language: | English |
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Faculty of Veterinary Medicine, Beni-Suef University
2005-12-01
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| Series: | Journal of Veterinary Medical Research |
| Subjects: | |
| Online Access: | https://jvmr.journals.ekb.eg/article_77994.html |
| _version_ | 1831654559779389440 |
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| author | A. M. Daoud R. A. Diab S. M. Aboul Saoud S. M. Zeidan F. F. Zaki |
| author_facet | A. M. Daoud R. A. Diab S. M. Aboul Saoud S. M. Zeidan F. F. Zaki |
| author_sort | A. M. Daoud |
| collection | DOAJ |
| description | A conclusive study was conducted for preparation and evaluation of combined
inactivated entero-4 vaccine containing bovine rotavirus (BRV), bovine coronavirus
(BCV), E. coli K99 and toxoid of C. perfringens type "C". Laboratory and field evaluations were conducted on laboratory animals, calves and late pregnant cows with monitoring the active and passive antibodies in vaccinated cows and their offspring respectively. Laboratory evaluation proved purity, safety and high efficacy of the vaccine without interference between different vaccine ingredients. Field evaluation gave satisfactory results when pregnant cows vaccinated at late stage of pregnancy with high neutralizing antibody titers against BRV, BCV and C. perfringens as well as high E. coli agglutinating titers. Maternal immunity passively protected offspring during the critical period of age and remained protected till the end of sampling time (30th day post parturition). |
| first_indexed | 2024-12-19T16:30:22Z |
| format | Article |
| id | doaj.art-c093ca79c5734e9aa2155ac772d0e49b |
| institution | Directory Open Access Journal |
| issn | 2357-0512 2357-0520 |
| language | English |
| last_indexed | 2024-12-19T16:30:22Z |
| publishDate | 2005-12-01 |
| publisher | Faculty of Veterinary Medicine, Beni-Suef University |
| record_format | Article |
| series | Journal of Veterinary Medical Research |
| spelling | doaj.art-c093ca79c5734e9aa2155ac772d0e49b2022-12-21T20:14:13ZengFaculty of Veterinary Medicine, Beni-Suef UniversityJournal of Veterinary Medical Research2357-05122357-05202005-12-01152232237Preparation and evaluation of combined inactivated vaccine containing rota, corona viruses, Escherichia coli bacterin and Clostridium perfringens type Ctoxoid (Entero-4)A. M. Daoud0 R. A. Diab1 S. M. Aboul Saoud2 S. M. Zeidan3 F. F. Zaki4Veterinary Serum and Vaccine Research Institute, Abbassia, Cairo, EgyptVeterinary Serum and Vaccine Research Institute, Abbassia, Cairo, EgyptVeterinary Serum and Vaccine Research Institute, Abbassia, Cairo, EgyptVeterinary Serum and Vaccine Research Institute, Abbassia, Cairo, EgyptCentral Laboratory for Evaluation of Veterinary Biologics, Abbassia, Cairo, EgyptA conclusive study was conducted for preparation and evaluation of combined inactivated entero-4 vaccine containing bovine rotavirus (BRV), bovine coronavirus (BCV), E. coli K99 and toxoid of C. perfringens type "C". Laboratory and field evaluations were conducted on laboratory animals, calves and late pregnant cows with monitoring the active and passive antibodies in vaccinated cows and their offspring respectively. Laboratory evaluation proved purity, safety and high efficacy of the vaccine without interference between different vaccine ingredients. Field evaluation gave satisfactory results when pregnant cows vaccinated at late stage of pregnancy with high neutralizing antibody titers against BRV, BCV and C. perfringens as well as high E. coli agglutinating titers. Maternal immunity passively protected offspring during the critical period of age and remained protected till the end of sampling time (30th day post parturition).https://jvmr.journals.ekb.eg/article_77994.htmlpreparation; evaluation; vaccine; inactivated; corona; viruses; escherichia coli; bacterin; toxoid |
| spellingShingle | A. M. Daoud R. A. Diab S. M. Aboul Saoud S. M. Zeidan F. F. Zaki Preparation and evaluation of combined inactivated vaccine containing rota, corona viruses, Escherichia coli bacterin and Clostridium perfringens type Ctoxoid (Entero-4) Journal of Veterinary Medical Research preparation; evaluation; vaccine; inactivated; corona; viruses; escherichia coli; bacterin; toxoid |
| title | Preparation and evaluation of combined inactivated vaccine containing rota, corona viruses, Escherichia coli bacterin and Clostridium perfringens type Ctoxoid (Entero-4) |
| title_full | Preparation and evaluation of combined inactivated vaccine containing rota, corona viruses, Escherichia coli bacterin and Clostridium perfringens type Ctoxoid (Entero-4) |
| title_fullStr | Preparation and evaluation of combined inactivated vaccine containing rota, corona viruses, Escherichia coli bacterin and Clostridium perfringens type Ctoxoid (Entero-4) |
| title_full_unstemmed | Preparation and evaluation of combined inactivated vaccine containing rota, corona viruses, Escherichia coli bacterin and Clostridium perfringens type Ctoxoid (Entero-4) |
| title_short | Preparation and evaluation of combined inactivated vaccine containing rota, corona viruses, Escherichia coli bacterin and Clostridium perfringens type Ctoxoid (Entero-4) |
| title_sort | preparation and evaluation of combined inactivated vaccine containing rota corona viruses escherichia coli bacterin and clostridium perfringens type ctoxoid entero 4 |
| topic | preparation; evaluation; vaccine; inactivated; corona; viruses; escherichia coli; bacterin; toxoid |
| url | https://jvmr.journals.ekb.eg/article_77994.html |
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