Hypomethylation and expression of <it>BEX2, IGSF4 </it>and <it>TIMP3 </it>indicative of <it>MLL </it>translocations in Acute Myeloid Leukemia

Hypomethylation and expression of <it>BEX2, IGSF4 </it>and <it>TIMP3 </it>indicative of <it>MLL </it>translocations in Acute Myeloid Leukemia

<p>Abstract</p> <p>Background</p> <p>Translocations of the <it>Mixed Lineage Leukemia </it>(<it>MLL</it>) gene occur in a subset (5%) of acute myeloid leukemias (AML), and in mixed phenotype acute leukemias in infancy - a disease with extremely p...

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Bibliographic Details
Main Authors: Slany Robert, Scherr Michaela, Marschalek Rolf, Meyer Claus, Dirks Wilhelm G, Röhrs Sonja, Wallace Andrew, Drexler Hans G, Quentmeier Hilmar
Format: Article
Language:English
Published: BMC 2009-10-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/8/1/86

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