Antimicrobial and Seasonal Evaluation of the Carvacrol-Chemotype Oil from Lippia origanoides Kunth.
This study evaluated the influence of seasonal variation on the yield and composition of essential oil of Lippia origanoides occurring in the Middle Rio Amazonas, Brazil, and the impact on its antimicrobial potential. The average oil yield was 1.7% ± 0.2% in the rainy season and 1.6% ± 0.3% in the d...
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MDPI AG
2015-01-01
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| Series: | Molecules |
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| Online Access: | http://www.mdpi.com/1420-3049/20/2/1860 |
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| author | Sandra Layse F. Sarrazin Leomara Andrade da Silva Ana Paula F. de Assunção Ricardo B. Oliveira Victor Y. P. Calao Rodrigo da Silva Elena E. Stashenko José Guilherme S. Maia Rosa Helena V. Mourão |
| author_facet | Sandra Layse F. Sarrazin Leomara Andrade da Silva Ana Paula F. de Assunção Ricardo B. Oliveira Victor Y. P. Calao Rodrigo da Silva Elena E. Stashenko José Guilherme S. Maia Rosa Helena V. Mourão |
| author_sort | Sandra Layse F. Sarrazin |
| collection | DOAJ |
| description | This study evaluated the influence of seasonal variation on the yield and composition of essential oil of Lippia origanoides occurring in the Middle Rio Amazonas, Brazil, and the impact on its antimicrobial potential. The average oil yield was 1.7% ± 0.2% in the rainy season and 1.6% ± 0.3% in the dry season. Some correlations with climatic parameters were observed. The major components were carvacrol (rainy, 43.5% ± 1.9%; dry, 41.4% ± 2.04%), thymol (rainy, 10.7% ± 1.1%; dry, 10.6% ± 0.9%), p-cymene (rainy, 9.8% ± 0.7%; dry, 10.0% ± 1.4%) and p-methoxythymol (rainy, 9.6% ± 0.8%; dry, 10.4% ± 1.4%). It was found that the antibacterial activity of L. origanoides against Staphylococcus aureus and Escherichia coli was little influenced by the changes in oil composition due to seasonal variation. Against S. aureus, the oil Minimum Inhibitory Concentration (MIC) value was 1.25 μL/mL over ten months. Against E. coli, the oil MIC values ranged from 0.15 μL/mL to 0.31 μL/mL in different months of the year. The Minimum Bactericidal Concentration (MBC) value was 2.5 μL/mL against S. aureus and 1.25 μL/mL against E. coli. The results suggest that the antimicrobial activity identified in the oil remain unchanged for the full year, allowing its medicinal use without any risk of loss or absence of the active principles of the plant. |
| first_indexed | 2024-12-12T08:17:26Z |
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| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-12-12T08:17:26Z |
| publishDate | 2015-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-c098564327dc4f93a94fbe1cd79104c52022-12-22T00:31:32ZengMDPI AGMolecules1420-30492015-01-012021860187110.3390/molecules20021860molecules20021860Antimicrobial and Seasonal Evaluation of the Carvacrol-Chemotype Oil from Lippia origanoides Kunth.Sandra Layse F. Sarrazin0Leomara Andrade da Silva1Ana Paula F. de Assunção2Ricardo B. Oliveira3Victor Y. P. Calao4Rodrigo da Silva5Elena E. Stashenko6José Guilherme S. Maia7Rosa Helena V. Mourão8Programa de Pós-Graduação em Biodiversidade e Biotecnologia da Amazônia Legal, Universidade Federal do Amazonas, 60077-000 Manaus, BrazilPrograma de Pós-Graduação em Recursos Naturais da Amazônia, Universidade Federal do Oeste do Pará, 68135-110 Santarém, BrazilPrograma de Pós-Graduação em Recursos Naturais da Amazônia, Universidade Federal do Oeste do Pará, 68135-110 Santarém, BrazilPrograma de Pós-Graduação em Recursos Naturais da Amazônia, Universidade Federal do Oeste do Pará, 68135-110 Santarém, BrazilPrograma de Pós-Graduação em Recursos Naturais da Amazônia, Universidade Federal do Oeste do Pará, 68135-110 Santarém, BrazilPrograma de Pós-Graduação em Recursos Naturais da Amazônia, Universidade Federal do Oeste do Pará, 68135-110 Santarém, BrazilChromatography Laboratory, Research Center for Biomolecules, Industrial University of Santander, Bucaramanga 57, ColombiaPrograma de Pós-Graduação em Recursos Naturais da Amazônia, Universidade Federal do Oeste do Pará, 68135-110 Santarém, BrazilPrograma de Pós-Graduação em Biodiversidade e Biotecnologia da Amazônia Legal, Universidade Federal do Amazonas, 60077-000 Manaus, BrazilThis study evaluated the influence of seasonal variation on the yield and composition of essential oil of Lippia origanoides occurring in the Middle Rio Amazonas, Brazil, and the impact on its antimicrobial potential. The average oil yield was 1.7% ± 0.2% in the rainy season and 1.6% ± 0.3% in the dry season. Some correlations with climatic parameters were observed. The major components were carvacrol (rainy, 43.5% ± 1.9%; dry, 41.4% ± 2.04%), thymol (rainy, 10.7% ± 1.1%; dry, 10.6% ± 0.9%), p-cymene (rainy, 9.8% ± 0.7%; dry, 10.0% ± 1.4%) and p-methoxythymol (rainy, 9.6% ± 0.8%; dry, 10.4% ± 1.4%). It was found that the antibacterial activity of L. origanoides against Staphylococcus aureus and Escherichia coli was little influenced by the changes in oil composition due to seasonal variation. Against S. aureus, the oil Minimum Inhibitory Concentration (MIC) value was 1.25 μL/mL over ten months. Against E. coli, the oil MIC values ranged from 0.15 μL/mL to 0.31 μL/mL in different months of the year. The Minimum Bactericidal Concentration (MBC) value was 2.5 μL/mL against S. aureus and 1.25 μL/mL against E. coli. The results suggest that the antimicrobial activity identified in the oil remain unchanged for the full year, allowing its medicinal use without any risk of loss or absence of the active principles of the plant.http://www.mdpi.com/1420-3049/20/2/1860Lippia origanoidesVerbenaceaesalva-do-marajóessential oil compositionseasonal variationantimicrobial evaluation |
| spellingShingle | Sandra Layse F. Sarrazin Leomara Andrade da Silva Ana Paula F. de Assunção Ricardo B. Oliveira Victor Y. P. Calao Rodrigo da Silva Elena E. Stashenko José Guilherme S. Maia Rosa Helena V. Mourão Antimicrobial and Seasonal Evaluation of the Carvacrol-Chemotype Oil from Lippia origanoides Kunth. Molecules Lippia origanoides Verbenaceae salva-do-marajó essential oil composition seasonal variation antimicrobial evaluation |
| title | Antimicrobial and Seasonal Evaluation of the Carvacrol-Chemotype Oil from Lippia origanoides Kunth. |
| title_full | Antimicrobial and Seasonal Evaluation of the Carvacrol-Chemotype Oil from Lippia origanoides Kunth. |
| title_fullStr | Antimicrobial and Seasonal Evaluation of the Carvacrol-Chemotype Oil from Lippia origanoides Kunth. |
| title_full_unstemmed | Antimicrobial and Seasonal Evaluation of the Carvacrol-Chemotype Oil from Lippia origanoides Kunth. |
| title_short | Antimicrobial and Seasonal Evaluation of the Carvacrol-Chemotype Oil from Lippia origanoides Kunth. |
| title_sort | antimicrobial and seasonal evaluation of the carvacrol chemotype oil from lippia origanoides kunth |
| topic | Lippia origanoides Verbenaceae salva-do-marajó essential oil composition seasonal variation antimicrobial evaluation |
| url | http://www.mdpi.com/1420-3049/20/2/1860 |
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