The expression profiles of CD47 in the tumor microenvironment of salivary gland cancers: a next step in histology-driven immunotherapy

The expression profiles of CD47 in the tumor microenvironment of salivary gland cancers: a next step in histology-driven immunotherapy

Abstract Background Salivary gland carcinomas (SGC) are extremely rare malignancies with only limited treatment options for the metastatic phase of the disease. Treatment with anti-CD47 antibodies could represent a potent therapy for SGCs by promoting the phagocytic clearance of tumor cells through...

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Bibliographic Details
Main Authors: Michal Votava, Robin Bartolini, Linda Capkova, Jitka Smetanova, Vachtenheim Jiri, Martin Kuchar, David Kalfert, Jan Plzak, Jirina Bartunkova, Zuzana Strizova
Format: Article
Language:English
Published: BMC 2022-09-01
Series:BMC Cancer
Subjects:
Oral Cancer
Immunotherapy
Tumor microenvironment
CD47
Don’t eat me signal
Mucoepidermoid carcinoma
Online Access:https://doi.org/10.1186/s12885-022-10114-4

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