Safety and efficacy of pyronaridine–artesunate paediatric granules in the treatment of uncomplicated malaria in children: insights from randomized clinical trials and a real-world study

Safety and efficacy of pyronaridine–artesunate paediatric granules in the treatment of uncomplicated malaria in children: insights from randomized clinical trials and a real-world study

Abstract Background Children are particularly at risk of malaria. This analysis consolidates the clinical data for pyronaridine–artesunate (PA) paediatric granules in children from three randomized clinical trials and a real-world study (CANTAM). Methods An integrated safety analysis of individual p...

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Bibliographic Details
Main Authors: Michael Ramharter, Abdoulaye A. Djimde, Isabelle Borghini-Fuhrer, Robert Miller, Jangsik Shin, Adam Aspinall, Naomi Richardson, Martina Wibberg, Lawrence Fleckenstein, Sarah Arbe-Barnes, Stephan Duparc
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Malaria Journal
Subjects:
Malaria
Plasmodium falciparum
Pyronaridine–artesunate
Paediatric
Anti-malarial
Granule formulation
Online Access:https://doi.org/10.1186/s12936-024-04885-3

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