Reprogramming of Yersinia from virulent to persistent mode revealed by complex in vivo RNA-seq analysis.
We recently found that Yersinia pseudotuberculosis can be used as a model of persistent bacterial infections. We performed in vivo RNA-seq of bacteria in small cecal tissue biopsies at early and persistent stages of infection to determine strategies associated with persistence. Comprehensive analysi...
Main Authors: | Kemal Avican, Anna Fahlgren, Mikael Huss, Ann Kathrin Heroven, Michael Beckstette, Petra Dersch, Maria Fällman |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-01-01
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Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC4295882?pdf=render |
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