Genome editing iPSC to purposing enhancement of induce CD8 killer T cell function for regenerative immunotherapy

Genome editing iPSC to purposing enhancement of induce CD8 killer T cell function for regenerative immunotherapy

Abstract In recent years, immunotherapy has become a standard cancer therapy, joining surgery, chemotherapy, and radiation therapy. This therapeutic approach involves the use of patient-derived antigen-specific T cells or genetically modified T cells engineered with chimeric antigen receptors (CAR)...

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Bibliographic Details
Main Authors: Sota Kurihara, Akihiro Ishikawa, Shin Kaneko
Format: Article
Language:English
Published: BMC 2024-04-01
Series:Inflammation and Regeneration
Subjects:
CD8 + T cell
Chimeric antigen receptor
Genome editing
Immunotherapy
iPSC
Online Access:https://doi.org/10.1186/s41232-024-00328-3

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