Blood culture-negative endocarditis caused by Tropheryma whipplei: a case report of Whipple’s endocarditis

Case description: A 67-year-old man was admitted with progressive heart failure, due to blood culture-negative endocarditis of the aortic valve. In early course, urgent aortic valve replacement was needed. A polymerase chain reaction test (PCR) on samples of the explanted aortic valve revealed Troph...

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Main Authors: Silke Knol, Rogier L Nijhuis, Felix Geeraedts, Gerard Linssen
Format: Article
Language:English
Published: SMC MEDIA SRL 2021-05-01
Series:European Journal of Case Reports in Internal Medicine
Subjects:
Online Access:https://www.ejcrim.com/index.php/EJCRIM/article/view/2596
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author Silke Knol
Rogier L Nijhuis
Felix Geeraedts
Gerard Linssen
author_facet Silke Knol
Rogier L Nijhuis
Felix Geeraedts
Gerard Linssen
author_sort Silke Knol
collection DOAJ
description Case description: A 67-year-old man was admitted with progressive heart failure, due to blood culture-negative endocarditis of the aortic valve. In early course, urgent aortic valve replacement was needed. A polymerase chain reaction test (PCR) on samples of the explanted aortic valve revealed Tropheryma whipplei. He received ceftriaxone, followed by long-term co-trimoxazole. Recent arthralgia may have been a diagnostic clue. Conclusion: Whipple’s endocarditis should be assessed in patients with arthralgia and blood culture-negative endocarditis (BCNIE).
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spelling doaj.art-c0a2fcc6787c4064a1cf3481144c29722022-12-21T22:53:09ZengSMC MEDIA SRLEuropean Journal of Case Reports in Internal Medicine2284-25942021-05-0110.12890/2021_0025962212Blood culture-negative endocarditis caused by Tropheryma whipplei: a case report of Whipple’s endocarditisSilke Knol0Rogier L Nijhuis1Felix Geeraedts2Gerard Linssen3Department of Cardiology, Hospital Group Twente (ZGT), Almelo and Hengelo, The NetherlandsDepartment of Cardiology, Hospital Group Twente (ZGT), Almelo and Hengelo, The NetherlandsLaboratory Microbiology Twente Achterhoek (LabMicTA), Hengelo, The NetherlandsDepartment of Cardiology, Hospital Group Twente (ZGT), Almelo and Hengelo, The NetherlandsCase description: A 67-year-old man was admitted with progressive heart failure, due to blood culture-negative endocarditis of the aortic valve. In early course, urgent aortic valve replacement was needed. A polymerase chain reaction test (PCR) on samples of the explanted aortic valve revealed Tropheryma whipplei. He received ceftriaxone, followed by long-term co-trimoxazole. Recent arthralgia may have been a diagnostic clue. Conclusion: Whipple’s endocarditis should be assessed in patients with arthralgia and blood culture-negative endocarditis (BCNIE).https://www.ejcrim.com/index.php/EJCRIM/article/view/2596whipple’s endocarditistropheryma whippleiblood culture-negative endocarditis
spellingShingle Silke Knol
Rogier L Nijhuis
Felix Geeraedts
Gerard Linssen
Blood culture-negative endocarditis caused by Tropheryma whipplei: a case report of Whipple’s endocarditis
European Journal of Case Reports in Internal Medicine
whipple’s endocarditis
tropheryma whipplei
blood culture-negative endocarditis
title Blood culture-negative endocarditis caused by Tropheryma whipplei: a case report of Whipple’s endocarditis
title_full Blood culture-negative endocarditis caused by Tropheryma whipplei: a case report of Whipple’s endocarditis
title_fullStr Blood culture-negative endocarditis caused by Tropheryma whipplei: a case report of Whipple’s endocarditis
title_full_unstemmed Blood culture-negative endocarditis caused by Tropheryma whipplei: a case report of Whipple’s endocarditis
title_short Blood culture-negative endocarditis caused by Tropheryma whipplei: a case report of Whipple’s endocarditis
title_sort blood culture negative endocarditis caused by tropheryma whipplei a case report of whipple s endocarditis
topic whipple’s endocarditis
tropheryma whipplei
blood culture-negative endocarditis
url https://www.ejcrim.com/index.php/EJCRIM/article/view/2596
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AT felixgeeraedts bloodculturenegativeendocarditiscausedbytropherymawhippleiacasereportofwhipplesendocarditis
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