Usefulness and limitations of taste sensors in the evaluation of palatability and taste-masking in oral dosage forms

The purpose of this review is to discuss the advantages and limitations of taste sensors in the evaluation of the taste of palatability of different oral dosage forms. First, we consider some ways in which the palatability of various pharmaceutical formulations including orally disintegrating tablet...

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Main Authors: Tamami Haraguchi, Miyako Yoshida, Honami Kojima, Takahiro Uchida
Format: Article
Language:English
Published: Elsevier 2016-08-01
Series:Asian Journal of Pharmaceutical Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1818087616300101
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author Tamami Haraguchi
Miyako Yoshida
Honami Kojima
Takahiro Uchida
author_facet Tamami Haraguchi
Miyako Yoshida
Honami Kojima
Takahiro Uchida
author_sort Tamami Haraguchi
collection DOAJ
description The purpose of this review is to discuss the advantages and limitations of taste sensors in the evaluation of the taste of palatability of different oral dosage forms. First, we consider some ways in which the palatability of various pharmaceutical formulations including orally disintegrating tablets (ODTs) are tested using two different taste sensors. Second, we focus on the evaluation of palatability of ODTs. We compare the usefulness of three pieces of apparatus for estimating the disintegration time of ODTs. Finally, we compare the characteristics of the two taste sensors in the evaluation of palatability of various kinds of drug formulations.
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spelling doaj.art-c0a4298b5a994532a65c564dea2b182d2022-12-21T17:31:19ZengElsevierAsian Journal of Pharmaceutical Sciences1818-08762016-08-0111447948510.1016/j.ajps.2016.03.001Usefulness and limitations of taste sensors in the evaluation of palatability and taste-masking in oral dosage formsTamami HaraguchiMiyako YoshidaHonami KojimaTakahiro UchidaThe purpose of this review is to discuss the advantages and limitations of taste sensors in the evaluation of the taste of palatability of different oral dosage forms. First, we consider some ways in which the palatability of various pharmaceutical formulations including orally disintegrating tablets (ODTs) are tested using two different taste sensors. Second, we focus on the evaluation of palatability of ODTs. We compare the usefulness of three pieces of apparatus for estimating the disintegration time of ODTs. Finally, we compare the characteristics of the two taste sensors in the evaluation of palatability of various kinds of drug formulations.http://www.sciencedirect.com/science/article/pii/S1818087616300101PalatabilityTaste sensorOrally disintegrating tablet (ODT)Disintegration timeDrug formulation
spellingShingle Tamami Haraguchi
Miyako Yoshida
Honami Kojima
Takahiro Uchida
Usefulness and limitations of taste sensors in the evaluation of palatability and taste-masking in oral dosage forms
Asian Journal of Pharmaceutical Sciences
Palatability
Taste sensor
Orally disintegrating tablet (ODT)
Disintegration time
Drug formulation
title Usefulness and limitations of taste sensors in the evaluation of palatability and taste-masking in oral dosage forms
title_full Usefulness and limitations of taste sensors in the evaluation of palatability and taste-masking in oral dosage forms
title_fullStr Usefulness and limitations of taste sensors in the evaluation of palatability and taste-masking in oral dosage forms
title_full_unstemmed Usefulness and limitations of taste sensors in the evaluation of palatability and taste-masking in oral dosage forms
title_short Usefulness and limitations of taste sensors in the evaluation of palatability and taste-masking in oral dosage forms
title_sort usefulness and limitations of taste sensors in the evaluation of palatability and taste masking in oral dosage forms
topic Palatability
Taste sensor
Orally disintegrating tablet (ODT)
Disintegration time
Drug formulation
url http://www.sciencedirect.com/science/article/pii/S1818087616300101
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