What Does Post-Exercise Proteinuria Tell Us About Kidneys?
Objectives. Post exercise proteinuria (PEP) is found in about 20–40% of sportsmen after intensive exercise. Urinary NGAL is a new marker of tubulointerstitial kidney damage. The relationship between PEP and uNGAL has not been defined yet. In presented study a resting uNGAL as a predictor o...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wydawnictwo Naukowe Uniwersytetu Szczecińskiego
2016-01-01
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| Series: | Central European Journal of Sport Sciences and Medicine |
| Subjects: | |
| Online Access: | https://wnus.edu.pl/cejssm/en/issue/124/article/1306/ |
| _version_ | 1828274924395954176 |
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| author | Jacek Januszczyk Karolina Kuźbicka Dominik Rachoń Wojciech Ratkowski Marcin Renke Patrycja Tkachenko-Rita Robert Urbański Wojciech Wołyniec Katarzyna Zorena |
| author_facet | Jacek Januszczyk Karolina Kuźbicka Dominik Rachoń Wojciech Ratkowski Marcin Renke Patrycja Tkachenko-Rita Robert Urbański Wojciech Wołyniec Katarzyna Zorena |
| author_sort | Jacek Januszczyk |
| collection | DOAJ |
| description | Objectives. Post exercise proteinuria (PEP) is found in about 20–40% of sportsmen after intensive exercise. Urinary NGAL is a new marker of tubulointerstitial kidney damage. The relationship between PEP and uNGAL has not been defined yet. In presented study a resting uNGAL as a predictor of PEP was analyzed. The changes of albuminuria after exercise were monitored to estimate a frequency and range of PEP. Methods. 40 amateur healthy runners (mean age 36.65 ±10.61 years) participating in 10-km run took part in the study. Before and after the competition urine was collected. NGAL, albumin and creatinine were subsequently measured in urine. uNGAL to creatinine ratio (NCR) and albumin to creatinine ratio (ACR) were calculated. Results. 28 participants (mean age 37.9 ±11.46, 19 M, 9 F) with uNGAL below 15 ng/ml before competition were analyzed. The increase of ACR was observed in every case. Mean post-exercise ACR was 104.55 ±123.1 mg/g and was significantly higher than pre-exercise ACR 6.33 ±5.86 mg/g (p < 0.0005). The positive correlation was found between resting NCR and post-exercise ACR (r = 0.60, p < 0.05). Conclusions. Resting uNGAL positively correlated with PEP. The possible explanation of these findings is that persons with PEP had some early, occult tubulointersitial kidney damage. It is speculated that those runners have higher risk of chronic kidney disease. |
| first_indexed | 2024-04-13T06:43:12Z |
| format | Article |
| id | doaj.art-c0a8c47c02914e1197b466fb7b317eb3 |
| institution | Directory Open Access Journal |
| issn | 2300-9705 2353-2807 |
| language | English |
| last_indexed | 2024-04-13T06:43:12Z |
| publishDate | 2016-01-01 |
| publisher | Wydawnictwo Naukowe Uniwersytetu Szczecińskiego |
| record_format | Article |
| series | Central European Journal of Sport Sciences and Medicine |
| spelling | doaj.art-c0a8c47c02914e1197b466fb7b317eb32022-12-22T02:57:41ZengWydawnictwo Naukowe Uniwersytetu SzczecińskiegoCentral European Journal of Sport Sciences and Medicine2300-97052353-28072016-01-011410.18276/cej.2016.2-11What Does Post-Exercise Proteinuria Tell Us About Kidneys?Jacek Januszczyk0Karolina Kuźbicka1Dominik Rachoń2Wojciech Ratkowski3Marcin Renke4Patrycja Tkachenko-Rita5Robert Urbański6Wojciech Wołyniec7Katarzyna Zorena8Department of Occupational and Internal Medicine, Institute of Maritime and Tropical Medicine, Gdynia, Medical University of Gdansk, PolandDepartment of Clinical and Experimental Endocrinology, Institute of Maritime and Tropical Medicine, Gdynia, Medical University of Gdańsk, PolandDepartment of Clinical and Experimental Endocrinology, Institute of Maritime and Tropical Medicine, Gdynia, Medical University of Gdańsk, PolandAcademy of Physical Education and Sport, Gdansk, PolandDepartment of Occupational and Internal Medicine, Institute of Maritime and Tropical Medicine, Gdynia, Medical University of Gdansk, PolandMedical Laboratories Bruss Group ALAB, Gdynia, PolandAcademy of Physical Education and Sport, Gdansk, PolandDepartment of Occupational and Internal Medicine, Institute of Maritime and Tropical Medicine, Gdynia, Medical University of Gdansk, PolandDepartment of Clinical and Experimental Endocrinology, Institute of Maritime and Tropical Medicine, Gdynia, Medical University of Gdańsk, PolandObjectives. Post exercise proteinuria (PEP) is found in about 20–40% of sportsmen after intensive exercise. Urinary NGAL is a new marker of tubulointerstitial kidney damage. The relationship between PEP and uNGAL has not been defined yet. In presented study a resting uNGAL as a predictor of PEP was analyzed. The changes of albuminuria after exercise were monitored to estimate a frequency and range of PEP. Methods. 40 amateur healthy runners (mean age 36.65 ±10.61 years) participating in 10-km run took part in the study. Before and after the competition urine was collected. NGAL, albumin and creatinine were subsequently measured in urine. uNGAL to creatinine ratio (NCR) and albumin to creatinine ratio (ACR) were calculated. Results. 28 participants (mean age 37.9 ±11.46, 19 M, 9 F) with uNGAL below 15 ng/ml before competition were analyzed. The increase of ACR was observed in every case. Mean post-exercise ACR was 104.55 ±123.1 mg/g and was significantly higher than pre-exercise ACR 6.33 ±5.86 mg/g (p < 0.0005). The positive correlation was found between resting NCR and post-exercise ACR (r = 0.60, p < 0.05). Conclusions. Resting uNGAL positively correlated with PEP. The possible explanation of these findings is that persons with PEP had some early, occult tubulointersitial kidney damage. It is speculated that those runners have higher risk of chronic kidney disease.https://wnus.edu.pl/cejssm/en/issue/124/article/1306/albuminuriachronic kidney diseasehealthrunning |
| spellingShingle | Jacek Januszczyk Karolina Kuźbicka Dominik Rachoń Wojciech Ratkowski Marcin Renke Patrycja Tkachenko-Rita Robert Urbański Wojciech Wołyniec Katarzyna Zorena What Does Post-Exercise Proteinuria Tell Us About Kidneys? Central European Journal of Sport Sciences and Medicine albuminuria chronic kidney disease health running |
| title | What Does Post-Exercise Proteinuria Tell Us About Kidneys? |
| title_full | What Does Post-Exercise Proteinuria Tell Us About Kidneys? |
| title_fullStr | What Does Post-Exercise Proteinuria Tell Us About Kidneys? |
| title_full_unstemmed | What Does Post-Exercise Proteinuria Tell Us About Kidneys? |
| title_short | What Does Post-Exercise Proteinuria Tell Us About Kidneys? |
| title_sort | what does post exercise proteinuria tell us about kidneys |
| topic | albuminuria chronic kidney disease health running |
| url | https://wnus.edu.pl/cejssm/en/issue/124/article/1306/ |
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