Epsilon PKC increases brain mitochondrial SIRT1 protein levels via heat shock protein 90 following ischemic preconditioning in rats.

Epsilon PKC increases brain mitochondrial SIRT1 protein levels via heat shock protein 90 following ischemic preconditioning in rats.

Ischemic preconditioning is a neuroprotective mechanism whereby a sublethal ischemic exposure is protective against a subsequent lethal ischemic attack. We previously demonstrated that SIRT1, a nuclear localized stress-activated deacetylase, is vital for ischemic preconditioning neuroprotection. How...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy: John W Thompson, Kunjan R Dave, Isabel Saul, Srinivasan V Narayanan, Miguel A Perez-Pinzon
Format: Artykuł
Język:English
Wydane: Public Library of Science (PLoS) 2013-01-01
Seria:PLoS ONE
Dostęp online:http://europepmc.org/articles/PMC3772907?pdf=render

Internet

http://europepmc.org/articles/PMC3772907?pdf=render

Podobne zapisy