Insights into diastolic function analyses using cardiac magnetic resonance imaging: impact of trabeculae and papillary muscles
Abstract Background This cardiovascular magnetic resonance (CMR) study investigates the impact of trabeculae and papillary muscles (TPM) on diastolic function parameters by differentiation of the time-volume curve. Differentiation causes additional problems, which is overcome by standardization. Met...
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| Format: | Article |
| Language: | English |
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SpringerOpen
2021-11-01
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| Series: | Insights into Imaging |
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| Online Access: | https://doi.org/10.1186/s13244-021-01104-4 |
| _version_ | 1818683925817458688 |
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| author | Bjoern P. Schoennagel Kai Müllerleile Enver Tahir Jitka Starekova Regine Grosse Jin Yamamura Peter Bannas Gerhard Adam Roland Fischer |
| author_facet | Bjoern P. Schoennagel Kai Müllerleile Enver Tahir Jitka Starekova Regine Grosse Jin Yamamura Peter Bannas Gerhard Adam Roland Fischer |
| author_sort | Bjoern P. Schoennagel |
| collection | DOAJ |
| description | Abstract Background This cardiovascular magnetic resonance (CMR) study investigates the impact of trabeculae and papillary muscles (TPM) on diastolic function parameters by differentiation of the time-volume curve. Differentiation causes additional problems, which is overcome by standardization. Methods Cine steady-state free-precession imaging at 1.5 T was performed in 40 healthy volunteers stratified for age (age range 7–78y). LV time-volume curves were assessed by software-assisted delineation of endocardial contours from short axis slices applying two different methods: (1) inclusion of TPM into the myocardium and (2) inclusion of TPM into the LV cavity blood volume. Diastolic function was assessed from the differentiated time-volume curves defining the early and atrial peaks, their filling rates, filling volumes, and further dedicated diastolic measures, respectively. Results Only inclusion of TPM into the myocardium allowed precise assessment of early and atrial peak filling rates (EPFR, APFR) with clear distinction of EPFR and APFR expressed by the minimum between the early and atrial peak (EAmin) (100% vs. 36% for EAmin < 0.8). Prediction of peak filling rate ratios (PFRR) and filling volume ratios (FVR) by age was superior with inclusion of TPM into the myocardium compared to inclusion into the blood pool (r 2 = 0.85 vs. r 2 = 0.56 and r 2 = 0.89 vs. r 2 = 0.66). Standardization problems were overcome by the introduction of a third phase (mid-diastole, apart from diastole and systole) and fitting of the early and atrial peaks in the differentiated time-volume curve. Conclusions Only LV volumetry with inclusion of TPM into the myocardium allows precise determination of diastolic measures and prevents methodological artifacts. |
| first_indexed | 2024-12-17T10:42:29Z |
| format | Article |
| id | doaj.art-c0ae9dd9eacb40eb83996ca944966e39 |
| institution | Directory Open Access Journal |
| issn | 1869-4101 |
| language | English |
| last_indexed | 2024-12-17T10:42:29Z |
| publishDate | 2021-11-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | Insights into Imaging |
| spelling | doaj.art-c0ae9dd9eacb40eb83996ca944966e392022-12-21T21:52:13ZengSpringerOpenInsights into Imaging1869-41012021-11-0112111010.1186/s13244-021-01104-4Insights into diastolic function analyses using cardiac magnetic resonance imaging: impact of trabeculae and papillary musclesBjoern P. Schoennagel0Kai Müllerleile1Enver Tahir2Jitka Starekova3Regine Grosse4Jin Yamamura5Peter Bannas6Gerhard Adam7Roland Fischer8Department of Diagnostic and Interventional Radiology and Nuclear Medicine, University Medical Center Hamburg-EppendorfDepartment of Cardiology, University Heart and Vascular Center, University Hospital Hamburg-EppendorfDepartment of Diagnostic and Interventional Radiology and Nuclear Medicine, University Medical Center Hamburg-EppendorfDepartment of Diagnostic and Interventional Radiology and Nuclear Medicine, University Medical Center Hamburg-EppendorfDepartment of Pediatric Hematology and Oncology, University Medical Center Hamburg-EppendorfDepartment of Diagnostic and Interventional Radiology and Nuclear Medicine, University Medical Center Hamburg-EppendorfDepartment of Diagnostic and Interventional Radiology and Nuclear Medicine, University Medical Center Hamburg-EppendorfDepartment of Diagnostic and Interventional Radiology and Nuclear Medicine, University Medical Center Hamburg-EppendorfDepartment of Diagnostic and Interventional Radiology and Nuclear Medicine, University Medical Center Hamburg-EppendorfAbstract Background This cardiovascular magnetic resonance (CMR) study investigates the impact of trabeculae and papillary muscles (TPM) on diastolic function parameters by differentiation of the time-volume curve. Differentiation causes additional problems, which is overcome by standardization. Methods Cine steady-state free-precession imaging at 1.5 T was performed in 40 healthy volunteers stratified for age (age range 7–78y). LV time-volume curves were assessed by software-assisted delineation of endocardial contours from short axis slices applying two different methods: (1) inclusion of TPM into the myocardium and (2) inclusion of TPM into the LV cavity blood volume. Diastolic function was assessed from the differentiated time-volume curves defining the early and atrial peaks, their filling rates, filling volumes, and further dedicated diastolic measures, respectively. Results Only inclusion of TPM into the myocardium allowed precise assessment of early and atrial peak filling rates (EPFR, APFR) with clear distinction of EPFR and APFR expressed by the minimum between the early and atrial peak (EAmin) (100% vs. 36% for EAmin < 0.8). Prediction of peak filling rate ratios (PFRR) and filling volume ratios (FVR) by age was superior with inclusion of TPM into the myocardium compared to inclusion into the blood pool (r 2 = 0.85 vs. r 2 = 0.56 and r 2 = 0.89 vs. r 2 = 0.66). Standardization problems were overcome by the introduction of a third phase (mid-diastole, apart from diastole and systole) and fitting of the early and atrial peaks in the differentiated time-volume curve. Conclusions Only LV volumetry with inclusion of TPM into the myocardium allows precise determination of diastolic measures and prevents methodological artifacts.https://doi.org/10.1186/s13244-021-01104-4Diastolic functionTrabeculae and papillary musclesCardiovascular magnetic resonance |
| spellingShingle | Bjoern P. Schoennagel Kai Müllerleile Enver Tahir Jitka Starekova Regine Grosse Jin Yamamura Peter Bannas Gerhard Adam Roland Fischer Insights into diastolic function analyses using cardiac magnetic resonance imaging: impact of trabeculae and papillary muscles Insights into Imaging Diastolic function Trabeculae and papillary muscles Cardiovascular magnetic resonance |
| title | Insights into diastolic function analyses using cardiac magnetic resonance imaging: impact of trabeculae and papillary muscles |
| title_full | Insights into diastolic function analyses using cardiac magnetic resonance imaging: impact of trabeculae and papillary muscles |
| title_fullStr | Insights into diastolic function analyses using cardiac magnetic resonance imaging: impact of trabeculae and papillary muscles |
| title_full_unstemmed | Insights into diastolic function analyses using cardiac magnetic resonance imaging: impact of trabeculae and papillary muscles |
| title_short | Insights into diastolic function analyses using cardiac magnetic resonance imaging: impact of trabeculae and papillary muscles |
| title_sort | insights into diastolic function analyses using cardiac magnetic resonance imaging impact of trabeculae and papillary muscles |
| topic | Diastolic function Trabeculae and papillary muscles Cardiovascular magnetic resonance |
| url | https://doi.org/10.1186/s13244-021-01104-4 |
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