AST-001 Improves Social Deficits and Restores Dopamine Neuron Activity in a Mouse Model of Autism

AST-001 Improves Social Deficits and Restores Dopamine Neuron Activity in a Mouse Model of Autism

Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder characterized by impaired social communication and social interaction, restricted and repetitive behavior, and interests. The core symptoms of ASD are associated with deficits in mesocorticolimbic dopamine pathways that project...

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Bibliographic Details
Main Authors: Ki Bum Um, Soyoung Kwak, Sun-Ha Cheon, JuHyun Kim, Su-Kyeong Hwang
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Biomedicines
Subjects:
ASD
social interaction
dopaminergic neuron
pacemaking
calcium-activated potassium channel
valproic acid
Online Access:https://www.mdpi.com/2227-9059/11/12/3283

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