TMT induces apoptosis and necroptosis in mouse kidneys through oxidative stress-induced activation of the NLRP3 inflammasome

TMT induces apoptosis and necroptosis in mouse kidneys through oxidative stress-induced activation of the NLRP3 inflammasome

Trimethyltin chloride (TMT) is an organotin heat stabilizer that is widely used in the production of plastics, and has strong toxicity. Here, the effect of trimethyltin chloride on mouse kidneys and its related mechanism were studied by taking TMT mouse with drinking water as a model. Histological e...

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Bibliographic Details
Main Authors: Xiao-Jing Liu, Yu-Qi Wang, Shao-Qian Shang, Shiwen Xu, Mengyao Guo
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Trimethyltin chloride
Oxidative stress
Inflammasomes
Apoptosis
Necroptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651322000070

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