Advances in Treatment Models of Advanced Gastric Cancer
The prognosis of advanced gastric cancer (AGC) is extremely poor, and the therapeutic effect of traditional palliative chemotherapy is far from satisfactory. To overcome this bottleneck, palliative surgery resection, perioperative chemotherapy combined with surgical resection, hyperthermic intraperi...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2022-09-01
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Series: | Technology in Cancer Research & Treatment |
Online Access: | https://doi.org/10.1177/15330338221090353 |
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author | Tao Li Yufang He Qinglei Zhong Jiang Yu Xinhua Chen |
author_facet | Tao Li Yufang He Qinglei Zhong Jiang Yu Xinhua Chen |
author_sort | Tao Li |
collection | DOAJ |
description | The prognosis of advanced gastric cancer (AGC) is extremely poor, and the therapeutic effect of traditional palliative chemotherapy is far from satisfactory. To overcome this bottleneck, palliative surgery resection, perioperative chemotherapy combined with surgical resection, hyperthermic intraperitoneal chemotherapy (HIPEC), pressurized intraperitoneal aerosol chemotherapy (PIPAC), radiation therapy, molecular-targeted therapy have been explored in AGC. Although considerable progress has been achieved, there is still no overwhelming therapeutic method. Due to the high heterogeneity of AGC, it is particularly vital to reshaped the paradigm of gastric cancer therapy according to the characteristics of clinical classifications and molecular subtypes. |
first_indexed | 2024-12-10T10:50:14Z |
format | Article |
id | doaj.art-c0b1a7e786a04c05a4d96ace68041040 |
institution | Directory Open Access Journal |
issn | 1533-0338 |
language | English |
last_indexed | 2024-12-10T10:50:14Z |
publishDate | 2022-09-01 |
publisher | SAGE Publishing |
record_format | Article |
series | Technology in Cancer Research & Treatment |
spelling | doaj.art-c0b1a7e786a04c05a4d96ace680410402022-12-22T01:52:03ZengSAGE PublishingTechnology in Cancer Research & Treatment1533-03382022-09-012110.1177/15330338221090353Advances in Treatment Models of Advanced Gastric CancerTao Li0Yufang He1Qinglei Zhong2Jiang Yu3Xinhua Chen4 Department of General Surgery, , , Guangzhou, China The First Clinical Medical School, , Guangzhou, Guangdong, China The First Clinical Medical School, , Guangzhou, Guangdong, China Department of General Surgery, , , Guangzhou, China Department of General Surgery, , , Guangzhou, ChinaThe prognosis of advanced gastric cancer (AGC) is extremely poor, and the therapeutic effect of traditional palliative chemotherapy is far from satisfactory. To overcome this bottleneck, palliative surgery resection, perioperative chemotherapy combined with surgical resection, hyperthermic intraperitoneal chemotherapy (HIPEC), pressurized intraperitoneal aerosol chemotherapy (PIPAC), radiation therapy, molecular-targeted therapy have been explored in AGC. Although considerable progress has been achieved, there is still no overwhelming therapeutic method. Due to the high heterogeneity of AGC, it is particularly vital to reshaped the paradigm of gastric cancer therapy according to the characteristics of clinical classifications and molecular subtypes.https://doi.org/10.1177/15330338221090353 |
spellingShingle | Tao Li Yufang He Qinglei Zhong Jiang Yu Xinhua Chen Advances in Treatment Models of Advanced Gastric Cancer Technology in Cancer Research & Treatment |
title | Advances in Treatment Models of Advanced Gastric Cancer |
title_full | Advances in Treatment Models of Advanced Gastric Cancer |
title_fullStr | Advances in Treatment Models of Advanced Gastric Cancer |
title_full_unstemmed | Advances in Treatment Models of Advanced Gastric Cancer |
title_short | Advances in Treatment Models of Advanced Gastric Cancer |
title_sort | advances in treatment models of advanced gastric cancer |
url | https://doi.org/10.1177/15330338221090353 |
work_keys_str_mv | AT taoli advancesintreatmentmodelsofadvancedgastriccancer AT yufanghe advancesintreatmentmodelsofadvancedgastriccancer AT qingleizhong advancesintreatmentmodelsofadvancedgastriccancer AT jiangyu advancesintreatmentmodelsofadvancedgastriccancer AT xinhuachen advancesintreatmentmodelsofadvancedgastriccancer |