Antibacterial Evaluation of Some Schiff Bases Derived from 2-Acetylpyridine and Their Metal Complexes
A series of Schiff bases derived from 2-acetylpyridne and their metal complexes were characterized by elemental analysis, NMR, FT-IR and UV-Vis spectral studies. The complexes were screened for anti-bacterial activity against Methicillin-resistant <em>Staphylococcus aureus</em&a...
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| Format: | Article |
| Language: | English |
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MDPI AG
2012-05-01
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| Series: | Molecules |
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| Online Access: | http://www.mdpi.com/1420-3049/17/5/5952 |
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| author | Thong Kwai Lin Chai Lay Ching Cher Lin Ooi A. Hamid A. Hadi Mahmood Ameen Abdulla Nura Suleiman Gwaram Hapipah Mohd Ali Hamid Khaledi |
| author_facet | Thong Kwai Lin Chai Lay Ching Cher Lin Ooi A. Hamid A. Hadi Mahmood Ameen Abdulla Nura Suleiman Gwaram Hapipah Mohd Ali Hamid Khaledi |
| author_sort | Thong Kwai Lin |
| collection | DOAJ |
| description | A series of Schiff bases derived from 2-acetylpyridne and their metal complexes were characterized by elemental analysis, NMR, FT-IR and UV-Vis spectral studies. The complexes were screened for anti-bacterial activity against Methicillin-resistant <em>Staphylococcus aureus</em> (MRSA), <em>Acinetobacter baumanni</em> (AC), <em>Klebsiella pneumonie</em> (KB) and <em>Pseudomonas aeruginosa</em> (PA) using the disc diffusion and micro broth dilution assays. Based on the overall results, the complexes showed the highest activities against MRSA while a weak antibacterial activity was observed against <em>A. baumanii</em> and <em>P. aeruginosa</em>. |
| first_indexed | 2024-12-10T18:43:15Z |
| format | Article |
| id | doaj.art-c0b6b64d43f3458687a7ef81aa7ff6ea |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-12-10T18:43:15Z |
| publishDate | 2012-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-c0b6b64d43f3458687a7ef81aa7ff6ea2022-12-22T01:37:36ZengMDPI AGMolecules1420-30492012-05-011755952597110.3390/molecules17055952Antibacterial Evaluation of Some Schiff Bases Derived from 2-Acetylpyridine and Their Metal ComplexesThong Kwai LinChai Lay ChingCher Lin OoiA. Hamid A. HadiMahmood Ameen AbdullaNura Suleiman GwaramHapipah Mohd AliHamid KhalediA series of Schiff bases derived from 2-acetylpyridne and their metal complexes were characterized by elemental analysis, NMR, FT-IR and UV-Vis spectral studies. The complexes were screened for anti-bacterial activity against Methicillin-resistant <em>Staphylococcus aureus</em> (MRSA), <em>Acinetobacter baumanni</em> (AC), <em>Klebsiella pneumonie</em> (KB) and <em>Pseudomonas aeruginosa</em> (PA) using the disc diffusion and micro broth dilution assays. Based on the overall results, the complexes showed the highest activities against MRSA while a weak antibacterial activity was observed against <em>A. baumanii</em> and <em>P. aeruginosa</em>.http://www.mdpi.com/1420-3049/17/5/5952Schiff basesmetal complexesx-ray crystallographyanti-bacteria |
| spellingShingle | Thong Kwai Lin Chai Lay Ching Cher Lin Ooi A. Hamid A. Hadi Mahmood Ameen Abdulla Nura Suleiman Gwaram Hapipah Mohd Ali Hamid Khaledi Antibacterial Evaluation of Some Schiff Bases Derived from 2-Acetylpyridine and Their Metal Complexes Molecules Schiff bases metal complexes x-ray crystallography anti-bacteria |
| title | Antibacterial Evaluation of Some Schiff Bases Derived from 2-Acetylpyridine and Their Metal Complexes |
| title_full | Antibacterial Evaluation of Some Schiff Bases Derived from 2-Acetylpyridine and Their Metal Complexes |
| title_fullStr | Antibacterial Evaluation of Some Schiff Bases Derived from 2-Acetylpyridine and Their Metal Complexes |
| title_full_unstemmed | Antibacterial Evaluation of Some Schiff Bases Derived from 2-Acetylpyridine and Their Metal Complexes |
| title_short | Antibacterial Evaluation of Some Schiff Bases Derived from 2-Acetylpyridine and Their Metal Complexes |
| title_sort | antibacterial evaluation of some schiff bases derived from 2 acetylpyridine and their metal complexes |
| topic | Schiff bases metal complexes x-ray crystallography anti-bacteria |
| url | http://www.mdpi.com/1420-3049/17/5/5952 |
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