Transcriptomic inspection revealed a possible pathway regulating the formation of the high-quality brush hair in Chinese Haimen goat (Capra hircus)
The high-quality brush hair, or Type III brush hair, is coarse hair but with a tip and little medulla, which uniquely grows in the cervical carina of Chinese Haimen goat (Capra hircus). To unveil the mechanism of the formation of Type III brush hair in Haimen goats, transcriptomic RNAseq technology...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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The Royal Society
2018-01-01
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| Series: | Royal Society Open Science |
| Subjects: | |
| Online Access: | https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.170907 |
| _version_ | 1818251159327997952 |
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| author | Dejun Ji Bo Yang Yongjun Li Miaoying Cai Wei Zhang Guohu Cheng Haiyan Guo |
| author_facet | Dejun Ji Bo Yang Yongjun Li Miaoying Cai Wei Zhang Guohu Cheng Haiyan Guo |
| author_sort | Dejun Ji |
| collection | DOAJ |
| description | The high-quality brush hair, or Type III brush hair, is coarse hair but with a tip and little medulla, which uniquely grows in the cervical carina of Chinese Haimen goat (Capra hircus). To unveil the mechanism of the formation of Type III brush hair in Haimen goats, transcriptomic RNAseq technology was used for screening of differentially expressed genes (DEGs) in the skin samples of the Type III and the non-Type III hair goats, and these DEGs were analysed by KEGG pathway analysis. The results showed that a total of 295 DEGs were obtained, mainly from three main functional types: cellular component, molecular function and biological process. These DEGs were mainly enriched in three KEGG pathways, such as protein processing in endoplasmic reticulum, MAPK, and complement and coagulation cascades. These DEGs gave hints to a possible mechanism, under which heat stress possibly initiated the formation. The study provided some useful biological information, which could give a new view about the roles of certain factors in hair growth and give hints on the mechanism of the formation of the Type III brush hair in Chinese Haimen goat. |
| first_indexed | 2024-12-12T16:03:51Z |
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| id | doaj.art-c0b7e914ccde448f8ad6eaa0bafa78d0 |
| institution | Directory Open Access Journal |
| issn | 2054-5703 |
| language | English |
| last_indexed | 2024-12-12T16:03:51Z |
| publishDate | 2018-01-01 |
| publisher | The Royal Society |
| record_format | Article |
| series | Royal Society Open Science |
| spelling | doaj.art-c0b7e914ccde448f8ad6eaa0bafa78d02022-12-22T00:19:21ZengThe Royal SocietyRoyal Society Open Science2054-57032018-01-015110.1098/rsos.170907170907Transcriptomic inspection revealed a possible pathway regulating the formation of the high-quality brush hair in Chinese Haimen goat (Capra hircus)Dejun JiBo YangYongjun LiMiaoying CaiWei ZhangGuohu ChengHaiyan GuoThe high-quality brush hair, or Type III brush hair, is coarse hair but with a tip and little medulla, which uniquely grows in the cervical carina of Chinese Haimen goat (Capra hircus). To unveil the mechanism of the formation of Type III brush hair in Haimen goats, transcriptomic RNAseq technology was used for screening of differentially expressed genes (DEGs) in the skin samples of the Type III and the non-Type III hair goats, and these DEGs were analysed by KEGG pathway analysis. The results showed that a total of 295 DEGs were obtained, mainly from three main functional types: cellular component, molecular function and biological process. These DEGs were mainly enriched in three KEGG pathways, such as protein processing in endoplasmic reticulum, MAPK, and complement and coagulation cascades. These DEGs gave hints to a possible mechanism, under which heat stress possibly initiated the formation. The study provided some useful biological information, which could give a new view about the roles of certain factors in hair growth and give hints on the mechanism of the formation of the Type III brush hair in Chinese Haimen goat.https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.170907goatbrush hairdifferentially expressed genesheat stress |
| spellingShingle | Dejun Ji Bo Yang Yongjun Li Miaoying Cai Wei Zhang Guohu Cheng Haiyan Guo Transcriptomic inspection revealed a possible pathway regulating the formation of the high-quality brush hair in Chinese Haimen goat (Capra hircus) Royal Society Open Science goat brush hair differentially expressed genes heat stress |
| title | Transcriptomic inspection revealed a possible pathway regulating the formation of the high-quality brush hair in Chinese Haimen goat (Capra hircus) |
| title_full | Transcriptomic inspection revealed a possible pathway regulating the formation of the high-quality brush hair in Chinese Haimen goat (Capra hircus) |
| title_fullStr | Transcriptomic inspection revealed a possible pathway regulating the formation of the high-quality brush hair in Chinese Haimen goat (Capra hircus) |
| title_full_unstemmed | Transcriptomic inspection revealed a possible pathway regulating the formation of the high-quality brush hair in Chinese Haimen goat (Capra hircus) |
| title_short | Transcriptomic inspection revealed a possible pathway regulating the formation of the high-quality brush hair in Chinese Haimen goat (Capra hircus) |
| title_sort | transcriptomic inspection revealed a possible pathway regulating the formation of the high quality brush hair in chinese haimen goat capra hircus |
| topic | goat brush hair differentially expressed genes heat stress |
| url | https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.170907 |
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