Neurotoxicology of alcohol: a bibliometric and science mapping analysis
Alcohol consumption is common in many societies and has increased considerably, resulting in many socioeconomic and public health problems. In this sense, studies have been carried out in order to understand the mechanisms involved in alcohol consumption and related harmful effects. This study aimed...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-08-01
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| Series: | Frontiers in Pharmacology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fphar.2023.1209616/full |
| _version_ | 1797767552459341824 |
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| author | Paulo Fernando Santos Mendes Daiane Claydes Baia-da-Silva Wallacy Watson Pereira Melo Leonardo Oliveira Bittencourt Renata Duarte Souza-Rodrigues Luanna Melo Pereira Fernandes Cristiane do Socorro Ferraz Maia Rafael Rodrigues Lima |
| author_facet | Paulo Fernando Santos Mendes Daiane Claydes Baia-da-Silva Wallacy Watson Pereira Melo Leonardo Oliveira Bittencourt Renata Duarte Souza-Rodrigues Luanna Melo Pereira Fernandes Cristiane do Socorro Ferraz Maia Rafael Rodrigues Lima |
| author_sort | Paulo Fernando Santos Mendes |
| collection | DOAJ |
| description | Alcohol consumption is common in many societies and has increased considerably, resulting in many socioeconomic and public health problems. In this sense, studies have been carried out in order to understand the mechanisms involved in alcohol consumption and related harmful effects. This study aimed to identify and map the knowledge and to perform bibliometric analysis of the neurotoxicology of alcohol based on the 100 most cited articles. A search was carried out in the Web of Science Core Collection database and information was extracted regarding the journal, authors, keywords, year of publication, number of citations, country and continent of the corresponding author. For each selected manuscript, the study design, alcohol exposure model, dose, period of exposure, and effect on the central nervous system and research hotspots were mapped. The journal with the highest number of publications was Alcoholism: Clinical and Experimental Research (n = 11 papers), the author who contributed the most was Crews FT (n = 8 papers), the studies had a total of 288 keywords and 75% of the publications were from the United States of America. The experimental studies evaluated the effects of prenatal and postnatal exposure and were conducted in rats and mice using doses ranging from 2.5 to 14 g/kg/day, with administration by subcutaneous, intraperitoneal, intragastric, or inhalation route or with free access through drinking bottles. Among the studies mapped, the oldest one (1989) aimed to understand the systemic damage and mechanisms of action involved, while the most recent focused on understanding the receptors and mechanisms involved in addiction, as well as genetic factors. Our results show the panorama of the most widespread scientific production in the scientific community on the neurotoxicology of ethanol, a high prevalence was observed in studies that addressed fetal alcohol syndrome and/or the effects of ethanol on neurodevelopment. |
| first_indexed | 2024-03-12T20:40:30Z |
| format | Article |
| id | doaj.art-c0b90e699be94492b756c0d1252d46d1 |
| institution | Directory Open Access Journal |
| issn | 1663-9812 |
| language | English |
| last_indexed | 2024-03-12T20:40:30Z |
| publishDate | 2023-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pharmacology |
| spelling | doaj.art-c0b90e699be94492b756c0d1252d46d12023-08-01T10:56:12ZengFrontiers Media S.A.Frontiers in Pharmacology1663-98122023-08-011410.3389/fphar.2023.12096161209616Neurotoxicology of alcohol: a bibliometric and science mapping analysisPaulo Fernando Santos Mendes0Daiane Claydes Baia-da-Silva1Wallacy Watson Pereira Melo2Leonardo Oliveira Bittencourt3Renata Duarte Souza-Rodrigues4Luanna Melo Pereira Fernandes5Cristiane do Socorro Ferraz Maia6Rafael Rodrigues Lima7Laboratory of Functional and Structural Biology, Institute of Biological Sciences, Federal University of Pará, Belém, BrazilLaboratory of Functional and Structural Biology, Institute of Biological Sciences, Federal University of Pará, Belém, BrazilLaboratory of Functional and Structural Biology, Institute of Biological Sciences, Federal University of Pará, Belém, BrazilLaboratory of Functional and Structural Biology, Institute of Biological Sciences, Federal University of Pará, Belém, BrazilLaboratory of Functional and Structural Biology, Institute of Biological Sciences, Federal University of Pará, Belém, BrazilDepartment of Morphology and Physiological Sciences, Center of Sciences Biological and Health, State University of Pará, Belém, BrazilLaboratory of Functional and Structural Biology, Institute of Biological Sciences, Federal University of Pará, Belém, BrazilLaboratory of Functional and Structural Biology, Institute of Biological Sciences, Federal University of Pará, Belém, BrazilAlcohol consumption is common in many societies and has increased considerably, resulting in many socioeconomic and public health problems. In this sense, studies have been carried out in order to understand the mechanisms involved in alcohol consumption and related harmful effects. This study aimed to identify and map the knowledge and to perform bibliometric analysis of the neurotoxicology of alcohol based on the 100 most cited articles. A search was carried out in the Web of Science Core Collection database and information was extracted regarding the journal, authors, keywords, year of publication, number of citations, country and continent of the corresponding author. For each selected manuscript, the study design, alcohol exposure model, dose, period of exposure, and effect on the central nervous system and research hotspots were mapped. The journal with the highest number of publications was Alcoholism: Clinical and Experimental Research (n = 11 papers), the author who contributed the most was Crews FT (n = 8 papers), the studies had a total of 288 keywords and 75% of the publications were from the United States of America. The experimental studies evaluated the effects of prenatal and postnatal exposure and were conducted in rats and mice using doses ranging from 2.5 to 14 g/kg/day, with administration by subcutaneous, intraperitoneal, intragastric, or inhalation route or with free access through drinking bottles. Among the studies mapped, the oldest one (1989) aimed to understand the systemic damage and mechanisms of action involved, while the most recent focused on understanding the receptors and mechanisms involved in addiction, as well as genetic factors. Our results show the panorama of the most widespread scientific production in the scientific community on the neurotoxicology of ethanol, a high prevalence was observed in studies that addressed fetal alcohol syndrome and/or the effects of ethanol on neurodevelopment.https://www.frontiersin.org/articles/10.3389/fphar.2023.1209616/fullalcohol abusecentral nervous systemalcoholalcoholismbibliometric |
| spellingShingle | Paulo Fernando Santos Mendes Daiane Claydes Baia-da-Silva Wallacy Watson Pereira Melo Leonardo Oliveira Bittencourt Renata Duarte Souza-Rodrigues Luanna Melo Pereira Fernandes Cristiane do Socorro Ferraz Maia Rafael Rodrigues Lima Neurotoxicology of alcohol: a bibliometric and science mapping analysis Frontiers in Pharmacology alcohol abuse central nervous system alcohol alcoholism bibliometric |
| title | Neurotoxicology of alcohol: a bibliometric and science mapping analysis |
| title_full | Neurotoxicology of alcohol: a bibliometric and science mapping analysis |
| title_fullStr | Neurotoxicology of alcohol: a bibliometric and science mapping analysis |
| title_full_unstemmed | Neurotoxicology of alcohol: a bibliometric and science mapping analysis |
| title_short | Neurotoxicology of alcohol: a bibliometric and science mapping analysis |
| title_sort | neurotoxicology of alcohol a bibliometric and science mapping analysis |
| topic | alcohol abuse central nervous system alcohol alcoholism bibliometric |
| url | https://www.frontiersin.org/articles/10.3389/fphar.2023.1209616/full |
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