Bestrophin-3 Expression in a Subpopulation of Astrocytes in the Neonatal Brain After Hypoxic-Ischemic Injury

Bestrophin-3 Expression in a Subpopulation of Astrocytes in the Neonatal Brain After Hypoxic-Ischemic Injury

Bestrophin-3, a potential candidate for a calcium-activated chloride channel, recently was suggested to have cell-protective functions. We studied the expression and alternative splicing of bestrophin-3 in neonatal mouse brain and after hypoxic-ischemic (HI) injury and in human neonatal brain sample...

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Bibliographic Details
Main Authors: Veronika Golubinskaya, Regina Vontell, Veena Supramaniam, Josephine Wyatt-Ashmead, Helena Gustafsson, Carina Mallard, Holger Nilsson
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Physiology
Subjects:
bestrophin-3 (Best3)
alternative splicing
astroglia
endoplasmic reticulum (ER) stress
hypoxia-ischemia
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.00023/full

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