Diabetes is accompanied by secretion of pro-atherosclerotic exosomes from vascular smooth muscle cells

Diabetes is accompanied by secretion of pro-atherosclerotic exosomes from vascular smooth muscle cells

Abstract Background Atherosclerosis is a common co-morbidity of type 2 diabetes mellitus. Monocyte recruitment by an activated endothelium and the pro-inflammatory activity of the resulting macrophages are critical components of atherosclerosis. Exosomal transfer of microRNAs has emerged as a paracr...

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Bibliographic Details
Main Authors: Heng Yu, Hunter F. Douglas, Donald Wathieu, Ryan A. Braun, Christine Edomwande, Daniel J. Lightell Jr., Thaidan Pham, Natasha C. Klingenberg, Shelia Pugh Bishop, Damir B. Khismatullin, T. Cooper Woods
Format: Article
Language:English
Published: BMC 2023-05-01
Series:Cardiovascular Diabetology
Subjects:
Exosomes
microRNA
Atherogenesis/atherosclerosis
Endothelial dysfunction
Macrophage activation
Vascular inflammation
Online Access:https://doi.org/10.1186/s12933-023-01833-4

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