A Review of Recent Advances in Robotic Cell Microinjection
Cell microinjection is a direct and effective way to transfer external materials into the cell. In the field of modern biomedicine, cell microinjection is very important, no matter in genetics, reproductive health, tumor therapy or others related research directions. Traditional manual cell microinj...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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IEEE
2020-01-01
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| Series: | IEEE Access |
| Subjects: | |
| Online Access: | https://ieeexplore.ieee.org/document/8950340/ |
| _version_ | 1818920803611181056 |
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| author | Ziqiang Chi Qingsong Xu Limin Zhu |
| author_facet | Ziqiang Chi Qingsong Xu Limin Zhu |
| author_sort | Ziqiang Chi |
| collection | DOAJ |
| description | Cell microinjection is a direct and effective way to transfer external materials into the cell. In the field of modern biomedicine, cell microinjection is very important, no matter in genetics, reproductive health, tumor therapy or others related research directions. Traditional manual cell microinjection has the disadvantages of low efficiency and low survival rate. In contrast, robotic cell microinjection can achieve precise and effective cell microinjection, and can be used in the injection of large quantities of cells. This paper reviews recent advances in robotic cell microinjection technologies. It summarizes the main approaches of key technologies and their advantages and disadvantages, such as cell identification, cell holding, precise positioning platform, cell injection strategy, sensors in cell microinjection, and cell modeling. The conclusion of the investigation is that the robotic cell microinjection has achieved remarkable results and still has great potential for further development. It is expected to be widely used in biomedicine and other fields to realize convenient, fast, and efficient microinjection operations of large number of individual cells. |
| first_indexed | 2024-12-20T01:27:33Z |
| format | Article |
| id | doaj.art-c0d0389924f049d0b648379278e476f1 |
| institution | Directory Open Access Journal |
| issn | 2169-3536 |
| language | English |
| last_indexed | 2024-12-20T01:27:33Z |
| publishDate | 2020-01-01 |
| publisher | IEEE |
| record_format | Article |
| series | IEEE Access |
| spelling | doaj.art-c0d0389924f049d0b648379278e476f12022-12-21T19:58:11ZengIEEEIEEE Access2169-35362020-01-0188520853210.1109/ACCESS.2020.29643058950340A Review of Recent Advances in Robotic Cell MicroinjectionZiqiang Chi0https://orcid.org/0000-0001-5811-2919Qingsong Xu1https://orcid.org/0000-0002-1700-322XLimin Zhu2https://orcid.org/0000-0003-3194-6731Department of Electromechanical Engineering, Faculty of Science and Technology, University of Macau, Macau, ChinaDepartment of Electromechanical Engineering, Faculty of Science and Technology, University of Macau, Macau, ChinaState Key Laboratory of Mechanical System and Vibration, School of Mechanical Engineering, Shanghai Jiao Tong University, Shanghai, ChinaCell microinjection is a direct and effective way to transfer external materials into the cell. In the field of modern biomedicine, cell microinjection is very important, no matter in genetics, reproductive health, tumor therapy or others related research directions. Traditional manual cell microinjection has the disadvantages of low efficiency and low survival rate. In contrast, robotic cell microinjection can achieve precise and effective cell microinjection, and can be used in the injection of large quantities of cells. This paper reviews recent advances in robotic cell microinjection technologies. It summarizes the main approaches of key technologies and their advantages and disadvantages, such as cell identification, cell holding, precise positioning platform, cell injection strategy, sensors in cell microinjection, and cell modeling. The conclusion of the investigation is that the robotic cell microinjection has achieved remarkable results and still has great potential for further development. It is expected to be widely used in biomedicine and other fields to realize convenient, fast, and efficient microinjection operations of large number of individual cells.https://ieeexplore.ieee.org/document/8950340/Robotic cell microinjectioncell identificationcell holdingprecise displacement platforminjection strategysensors in cell microinjection |
| spellingShingle | Ziqiang Chi Qingsong Xu Limin Zhu A Review of Recent Advances in Robotic Cell Microinjection IEEE Access Robotic cell microinjection cell identification cell holding precise displacement platform injection strategy sensors in cell microinjection |
| title | A Review of Recent Advances in Robotic Cell Microinjection |
| title_full | A Review of Recent Advances in Robotic Cell Microinjection |
| title_fullStr | A Review of Recent Advances in Robotic Cell Microinjection |
| title_full_unstemmed | A Review of Recent Advances in Robotic Cell Microinjection |
| title_short | A Review of Recent Advances in Robotic Cell Microinjection |
| title_sort | review of recent advances in robotic cell microinjection |
| topic | Robotic cell microinjection cell identification cell holding precise displacement platform injection strategy sensors in cell microinjection |
| url | https://ieeexplore.ieee.org/document/8950340/ |
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