Gut Microbiome Modulation for Preventing and Treating Pediatric Food Allergies
The increasing prevalence and severity of pediatric food allergies (FA) demands innovative preventive and therapeutic strategies. Emerging evidence suggests a pivotal role for the gut microbiome in modulating susceptibility to FA. Studies have demonstrated that alteration of gut microbiome could pre...
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Format: | Article |
Language: | English |
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MDPI AG
2020-07-01
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Series: | International Journal of Molecular Sciences |
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Online Access: | https://www.mdpi.com/1422-0067/21/15/5275 |
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author | Margherita Di Costanzo Laura Carucci Roberto Berni Canani Giacomo Biasucci |
author_facet | Margherita Di Costanzo Laura Carucci Roberto Berni Canani Giacomo Biasucci |
author_sort | Margherita Di Costanzo |
collection | DOAJ |
description | The increasing prevalence and severity of pediatric food allergies (FA) demands innovative preventive and therapeutic strategies. Emerging evidence suggests a pivotal role for the gut microbiome in modulating susceptibility to FA. Studies have demonstrated that alteration of gut microbiome could precede FA, and that particular microbial community structures early in life could influence also the disease course. The identification of gut microbiome features in pediatric FA patients is driving new prevention and treatment approaches. This review is focused on the potential role of the gut microbiome as a target for FA prevention and treatment. |
first_indexed | 2024-03-10T18:13:21Z |
format | Article |
id | doaj.art-c0d07bcd49e946beafc363741a23d497 |
institution | Directory Open Access Journal |
issn | 1661-6596 1422-0067 |
language | English |
last_indexed | 2024-03-10T18:13:21Z |
publishDate | 2020-07-01 |
publisher | MDPI AG |
record_format | Article |
series | International Journal of Molecular Sciences |
spelling | doaj.art-c0d07bcd49e946beafc363741a23d4972023-11-20T07:55:19ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672020-07-012115527510.3390/ijms21155275Gut Microbiome Modulation for Preventing and Treating Pediatric Food AllergiesMargherita Di Costanzo0Laura Carucci1Roberto Berni Canani2Giacomo Biasucci3Department of Pediatrics and Neonatology, Guglielmo da Saliceto Hospital, 29121 Piacenza, ItalyDepartment of Translational Medical Science-Pediatric Section, University “Federico II”, 80131 Naples, ItalyDepartment of Translational Medical Science-Pediatric Section, University “Federico II”, 80131 Naples, ItalyDepartment of Pediatrics and Neonatology, Guglielmo da Saliceto Hospital, 29121 Piacenza, ItalyThe increasing prevalence and severity of pediatric food allergies (FA) demands innovative preventive and therapeutic strategies. Emerging evidence suggests a pivotal role for the gut microbiome in modulating susceptibility to FA. Studies have demonstrated that alteration of gut microbiome could precede FA, and that particular microbial community structures early in life could influence also the disease course. The identification of gut microbiome features in pediatric FA patients is driving new prevention and treatment approaches. This review is focused on the potential role of the gut microbiome as a target for FA prevention and treatment.https://www.mdpi.com/1422-0067/21/15/5275gut microbiomefood allergydysbiosis |
spellingShingle | Margherita Di Costanzo Laura Carucci Roberto Berni Canani Giacomo Biasucci Gut Microbiome Modulation for Preventing and Treating Pediatric Food Allergies International Journal of Molecular Sciences gut microbiome food allergy dysbiosis |
title | Gut Microbiome Modulation for Preventing and Treating Pediatric Food Allergies |
title_full | Gut Microbiome Modulation for Preventing and Treating Pediatric Food Allergies |
title_fullStr | Gut Microbiome Modulation for Preventing and Treating Pediatric Food Allergies |
title_full_unstemmed | Gut Microbiome Modulation for Preventing and Treating Pediatric Food Allergies |
title_short | Gut Microbiome Modulation for Preventing and Treating Pediatric Food Allergies |
title_sort | gut microbiome modulation for preventing and treating pediatric food allergies |
topic | gut microbiome food allergy dysbiosis |
url | https://www.mdpi.com/1422-0067/21/15/5275 |
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