Plaque Erosion: A Distinctive Pathological Mechanism of Acute Coronary Syndrome

Plaque erosion (PE) is one of the most important pathological mechanisms underlying acute coronary syndrome (ACS). The incidence of PE is being increasingly recognized owing to the development and popularization of intracavitary imaging. Unlike traditional vulnerable plaques, eroded plaques have uni...

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Main Authors: Xing Luo, Ying Lv, Xiaoxuan Bai, Jinyu Qi, Xiuzhu Weng, Shaoyu Liu, Xiaoyi Bao, Haibo Jia, Bo Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2021.711453/full
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author Xing Luo
Xing Luo
Ying Lv
Ying Lv
Xiaoxuan Bai
Xiaoxuan Bai
Jinyu Qi
Jinyu Qi
Xiuzhu Weng
Xiuzhu Weng
Shaoyu Liu
Shaoyu Liu
Xiaoyi Bao
Xiaoyi Bao
Haibo Jia
Haibo Jia
Bo Yu
Bo Yu
author_facet Xing Luo
Xing Luo
Ying Lv
Ying Lv
Xiaoxuan Bai
Xiaoxuan Bai
Jinyu Qi
Jinyu Qi
Xiuzhu Weng
Xiuzhu Weng
Shaoyu Liu
Shaoyu Liu
Xiaoyi Bao
Xiaoyi Bao
Haibo Jia
Haibo Jia
Bo Yu
Bo Yu
author_sort Xing Luo
collection DOAJ
description Plaque erosion (PE) is one of the most important pathological mechanisms underlying acute coronary syndrome (ACS). The incidence of PE is being increasingly recognized owing to the development and popularization of intracavitary imaging. Unlike traditional vulnerable plaques, eroded plaques have unique pathological characteristics. Moreover, recent studies have revealed that there are differences in the physiopathological mechanisms, biomarkers, and clinical outcomes between PE and plaque rupture (PR). Accurate diagnosis and treatment of eroded plaques require an understanding of the pathogenesis of PE. In this review, we summarize recent scientific discoveries of the pathological characteristics, mechanisms, biomarkers, clinical strategies, and prognosis in patients with PE.
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spelling doaj.art-c0d1d81a369c4ac7acbe2240f9baf60b2022-12-21T18:57:19ZengFrontiers Media S.A.Frontiers in Cardiovascular Medicine2297-055X2021-09-01810.3389/fcvm.2021.711453711453Plaque Erosion: A Distinctive Pathological Mechanism of Acute Coronary SyndromeXing Luo0Xing Luo1Ying Lv2Ying Lv3Xiaoxuan Bai4Xiaoxuan Bai5Jinyu Qi6Jinyu Qi7Xiuzhu Weng8Xiuzhu Weng9Shaoyu Liu10Shaoyu Liu11Xiaoyi Bao12Xiaoyi Bao13Haibo Jia14Haibo Jia15Bo Yu16Bo Yu17Department of Cardiology, 2nd Affiliated Hospital of Harbin Medical University, Harbin, ChinaKey Laboratory of Myocardial Ischemia, Ministry of Education, Harbin Medical University, Harbin, ChinaDepartment of Cardiology, 2nd Affiliated Hospital of Harbin Medical University, Harbin, ChinaKey Laboratory of Myocardial Ischemia, Ministry of Education, Harbin Medical University, Harbin, ChinaDepartment of Cardiology, 2nd Affiliated Hospital of Harbin Medical University, Harbin, ChinaKey Laboratory of Myocardial Ischemia, Ministry of Education, Harbin Medical University, Harbin, ChinaDepartment of Cardiology, 2nd Affiliated Hospital of Harbin Medical University, Harbin, ChinaKey Laboratory of Myocardial Ischemia, Ministry of Education, Harbin Medical University, Harbin, ChinaDepartment of Cardiology, 2nd Affiliated Hospital of Harbin Medical University, Harbin, ChinaKey Laboratory of Myocardial Ischemia, Ministry of Education, Harbin Medical University, Harbin, ChinaKey Laboratory of Myocardial Ischemia, Ministry of Education, Harbin Medical University, Harbin, ChinaBin Xian People's Hospital, Harbin, ChinaDepartment of Cardiology, 2nd Affiliated Hospital of Harbin Medical University, Harbin, ChinaKey Laboratory of Myocardial Ischemia, Ministry of Education, Harbin Medical University, Harbin, ChinaDepartment of Cardiology, 2nd Affiliated Hospital of Harbin Medical University, Harbin, ChinaKey Laboratory of Myocardial Ischemia, Ministry of Education, Harbin Medical University, Harbin, ChinaDepartment of Cardiology, 2nd Affiliated Hospital of Harbin Medical University, Harbin, ChinaKey Laboratory of Myocardial Ischemia, Ministry of Education, Harbin Medical University, Harbin, ChinaPlaque erosion (PE) is one of the most important pathological mechanisms underlying acute coronary syndrome (ACS). The incidence of PE is being increasingly recognized owing to the development and popularization of intracavitary imaging. Unlike traditional vulnerable plaques, eroded plaques have unique pathological characteristics. Moreover, recent studies have revealed that there are differences in the physiopathological mechanisms, biomarkers, and clinical outcomes between PE and plaque rupture (PR). Accurate diagnosis and treatment of eroded plaques require an understanding of the pathogenesis of PE. In this review, we summarize recent scientific discoveries of the pathological characteristics, mechanisms, biomarkers, clinical strategies, and prognosis in patients with PE.https://www.frontiersin.org/articles/10.3389/fcvm.2021.711453/fullacute coronary syndromeplaque erosionplaque ruptureoptical coherence tomographybiomarker 2
spellingShingle Xing Luo
Xing Luo
Ying Lv
Ying Lv
Xiaoxuan Bai
Xiaoxuan Bai
Jinyu Qi
Jinyu Qi
Xiuzhu Weng
Xiuzhu Weng
Shaoyu Liu
Shaoyu Liu
Xiaoyi Bao
Xiaoyi Bao
Haibo Jia
Haibo Jia
Bo Yu
Bo Yu
Plaque Erosion: A Distinctive Pathological Mechanism of Acute Coronary Syndrome
Frontiers in Cardiovascular Medicine
acute coronary syndrome
plaque erosion
plaque rupture
optical coherence tomography
biomarker 2
title Plaque Erosion: A Distinctive Pathological Mechanism of Acute Coronary Syndrome
title_full Plaque Erosion: A Distinctive Pathological Mechanism of Acute Coronary Syndrome
title_fullStr Plaque Erosion: A Distinctive Pathological Mechanism of Acute Coronary Syndrome
title_full_unstemmed Plaque Erosion: A Distinctive Pathological Mechanism of Acute Coronary Syndrome
title_short Plaque Erosion: A Distinctive Pathological Mechanism of Acute Coronary Syndrome
title_sort plaque erosion a distinctive pathological mechanism of acute coronary syndrome
topic acute coronary syndrome
plaque erosion
plaque rupture
optical coherence tomography
biomarker 2
url https://www.frontiersin.org/articles/10.3389/fcvm.2021.711453/full
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