Study of cognitive functions in breast cancer patients: A case control study

Context: One-third of breast cancer survivors report difficulties with concentration, multi-tasking, and memory. Cognitive dysfunction can have an impact on quality of life by affecting activities of daily living, treatment compliance, interpersonal relationships, work/profession, and future. Aims:...

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Main Authors: Anupama Zeena Sequeira, K Krishnamurthy
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2014-01-01
Series:Muller Journal of Medical Sciences and Research
Subjects:
Online Access:http://www.mjmsr.net/article.asp?issn=0975-9727;year=2014;volume=5;issue=2;spage=129;epage=133;aulast=Sequeira
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author Anupama Zeena Sequeira
K Krishnamurthy
author_facet Anupama Zeena Sequeira
K Krishnamurthy
author_sort Anupama Zeena Sequeira
collection DOAJ
description Context: One-third of breast cancer survivors report difficulties with concentration, multi-tasking, and memory. Cognitive dysfunction can have an impact on quality of life by affecting activities of daily living, treatment compliance, interpersonal relationships, work/profession, and future. Aims: The objective of this study was to evaluate the cognitive functions in breast cancer patients. Settings and Design: This study was conducted in the outpatient department of Oncology from where the cases were recruited. The controls were patients attending other departments and not suffering from cancer. Materials and Methods: A total of 60 patients, 30 breast cancer patients and 30 non-cancer individuals patients matched for age, education were evaluated. Tools used were SMMSE, TMT-B, and DSST for evaluation of cognitive functions. Statistical Analysis: The various findings were analyzed using Chi-square test, Mann-Whitney Test, T test and ANOVA. Results: Breast cancer patients had highly statistically significant cognitive deficits in language and recall domains and significant deficit on orientation domain of SMMSE. They performed poorly in TMT-B, taking more time to complete the test which was statistically highly significant. No significant deficits were noted on the DSST test. Conclusion: Breast cancer patients show statistically significant cognitive deficits as compared to non cancer individuals.
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spelling doaj.art-c0d3eeff81cd43c0957a56b9a5f21f932022-12-22T02:42:54ZengWolters Kluwer Medknow PublicationsMuller Journal of Medical Sciences and Research0975-97272014-01-015212913310.4103/0975-9727.135745Study of cognitive functions in breast cancer patients: A case control studyAnupama Zeena SequeiraK KrishnamurthyContext: One-third of breast cancer survivors report difficulties with concentration, multi-tasking, and memory. Cognitive dysfunction can have an impact on quality of life by affecting activities of daily living, treatment compliance, interpersonal relationships, work/profession, and future. Aims: The objective of this study was to evaluate the cognitive functions in breast cancer patients. Settings and Design: This study was conducted in the outpatient department of Oncology from where the cases were recruited. The controls were patients attending other departments and not suffering from cancer. Materials and Methods: A total of 60 patients, 30 breast cancer patients and 30 non-cancer individuals patients matched for age, education were evaluated. Tools used were SMMSE, TMT-B, and DSST for evaluation of cognitive functions. Statistical Analysis: The various findings were analyzed using Chi-square test, Mann-Whitney Test, T test and ANOVA. Results: Breast cancer patients had highly statistically significant cognitive deficits in language and recall domains and significant deficit on orientation domain of SMMSE. They performed poorly in TMT-B, taking more time to complete the test which was statistically highly significant. No significant deficits were noted on the DSST test. Conclusion: Breast cancer patients show statistically significant cognitive deficits as compared to non cancer individuals.http://www.mjmsr.net/article.asp?issn=0975-9727;year=2014;volume=5;issue=2;spage=129;epage=133;aulast=SequeiraBreast cancercancercognition
spellingShingle Anupama Zeena Sequeira
K Krishnamurthy
Study of cognitive functions in breast cancer patients: A case control study
Muller Journal of Medical Sciences and Research
Breast cancer
cancer
cognition
title Study of cognitive functions in breast cancer patients: A case control study
title_full Study of cognitive functions in breast cancer patients: A case control study
title_fullStr Study of cognitive functions in breast cancer patients: A case control study
title_full_unstemmed Study of cognitive functions in breast cancer patients: A case control study
title_short Study of cognitive functions in breast cancer patients: A case control study
title_sort study of cognitive functions in breast cancer patients a case control study
topic Breast cancer
cancer
cognition
url http://www.mjmsr.net/article.asp?issn=0975-9727;year=2014;volume=5;issue=2;spage=129;epage=133;aulast=Sequeira
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