miR-122 Exerts Inhibitory Effects on Osteoblast Proliferation/Differentiation in Osteoporosis by Activating the PCP4-Mediated JNK Pathway

miR-122 Exerts Inhibitory Effects on Osteoblast Proliferation/Differentiation in Osteoporosis by Activating the PCP4-Mediated JNK Pathway

Osteoporosis is characterized by the reduction of bone mineral density and deterioration of bone quality which leads to high risk of fractures. Some microRNAs (miRNAs) have been confirmed as potential modulators of osteoblast differentiation to maintain bone mass maintenance. We aimed to clarify whe...

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Bibliographic Details
Main Authors:	Yi-Chen Meng, Tao Lin, Heng Jiang, Zheng Zhang, Lun Shu, Jia Yin, Xiao Ma, Ce Wang, Rui Gao, Xu-Hui Zhou
Format:	Article
Language:	English
Published:	Elsevier 2020-06-01
Series:	Molecular Therapy: Nucleic Acids
Subjects:	osteoporosis microRNA-122 PCP4 JNK signaling pathway osteoblasts proliferation
Online Access:	http://www.sciencedirect.com/science/article/pii/S2162253120300159

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