Inflammatory Control of Viral Infection
Inflammatory responses during virus infection differentially impact the host. Managing inflammatory responses is essential in controlling viral infection and related diseases. Recently, we identified a cellular anti-inflammatory mechanism, RIKA (Repression of IRF3-mediated inhibition of NF-κB activi...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-07-01
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| Series: | Viruses |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1999-4915/15/7/1579 |
| _version_ | 1797587256990498816 |
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| author | Sukanya Chakravarty Ritu Chakravarti Saurabh Chattopadhyay |
| author_facet | Sukanya Chakravarty Ritu Chakravarti Saurabh Chattopadhyay |
| author_sort | Sukanya Chakravarty |
| collection | DOAJ |
| description | Inflammatory responses during virus infection differentially impact the host. Managing inflammatory responses is essential in controlling viral infection and related diseases. Recently, we identified a cellular anti-inflammatory mechanism, RIKA (Repression of IRF3-mediated inhibition of NF-κB activity), which controls viral inflammation and pathogenesis. The RIKA function of IRF3 may be explored further in other inflammatory diseases beyond viral infection. |
| first_indexed | 2024-03-11T00:33:35Z |
| format | Article |
| id | doaj.art-c0d651128d2841cbadd9730017dd4169 |
| institution | Directory Open Access Journal |
| issn | 1999-4915 |
| language | English |
| last_indexed | 2024-03-11T00:33:35Z |
| publishDate | 2023-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Viruses |
| spelling | doaj.art-c0d651128d2841cbadd9730017dd41692023-11-18T21:45:41ZengMDPI AGViruses1999-49152023-07-01157157910.3390/v15071579Inflammatory Control of Viral InfectionSukanya Chakravarty0Ritu Chakravarti1Saurabh Chattopadhyay2Medical Microbiology and Immunology, University of Toledo College of Medicine and Life Sciences, Toledo, OH 43614, USAPhysiology and Pharmacology, University of Toledo College of Medicine and Life Sciences, Toledo, OH 43614, USAMedical Microbiology and Immunology, University of Toledo College of Medicine and Life Sciences, Toledo, OH 43614, USAInflammatory responses during virus infection differentially impact the host. Managing inflammatory responses is essential in controlling viral infection and related diseases. Recently, we identified a cellular anti-inflammatory mechanism, RIKA (Repression of IRF3-mediated inhibition of NF-κB activity), which controls viral inflammation and pathogenesis. The RIKA function of IRF3 may be explored further in other inflammatory diseases beyond viral infection.https://www.mdpi.com/1999-4915/15/7/1579IRF3NF-κBinflammationinnate immunityinterferonantiviral |
| spellingShingle | Sukanya Chakravarty Ritu Chakravarti Saurabh Chattopadhyay Inflammatory Control of Viral Infection Viruses IRF3 NF-κB inflammation innate immunity interferon antiviral |
| title | Inflammatory Control of Viral Infection |
| title_full | Inflammatory Control of Viral Infection |
| title_fullStr | Inflammatory Control of Viral Infection |
| title_full_unstemmed | Inflammatory Control of Viral Infection |
| title_short | Inflammatory Control of Viral Infection |
| title_sort | inflammatory control of viral infection |
| topic | IRF3 NF-κB inflammation innate immunity interferon antiviral |
| url | https://www.mdpi.com/1999-4915/15/7/1579 |
| work_keys_str_mv | AT sukanyachakravarty inflammatorycontrolofviralinfection AT rituchakravarti inflammatorycontrolofviralinfection AT saurabhchattopadhyay inflammatorycontrolofviralinfection |