PlA2 Polymorphism of Platelet Glycoprotein IIb/IIIa and C677T Polymorphism of Methylenetetrahydrofolate Reductase (<i>MTHFR</i>), but Not Factor V Leiden and Prothrombin G20210A Polymorphisms, Are Associated with More Severe Forms of Legg–Calvé–Perthes Disease

PlA2 Polymorphism of Platelet Glycoprotein IIb/IIIa and C677T Polymorphism of Methylenetetrahydrofolate Reductase (<i>MTHFR</i>), but Not Factor V Leiden and Prothrombin G20210A Polymorphisms, Are Associated with More Severe Forms of Legg–Calvé–Perthes Disease

The possible association of common polymorphic variants related to thrombophilia (the rs6025(A) allele encoding the Leiden mutation, rs1799963(A), i.e., the G20210A mutation of the prothrombin <i>F2</i> gene, the rs1801133(T) variant of the methylenetetrahydrofolate reductase (<i>M...

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Bibliographic Details
Main Authors: María Dolores García-Alfaro, María Isabel Pérez-Nuñez, María Teresa Amigo, Carmelo Arbona, María Ángeles Ballesteros, Domingo González-Lamuño
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Children
Subjects:
Legg–Calvé–Perthes disease
gene polymorphism
heritable thrombophilia
Online Access:https://www.mdpi.com/2227-9067/8/7/614

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