Maternal consumption of a high-fat diet modulates the inflammatory response in their offspring, mediated by the M1 muscarinic receptor

Maternal consumption of a high-fat diet modulates the inflammatory response in their offspring, mediated by the M1 muscarinic receptor

IntroductionHigh-fat diet (HFD) consumption is associated with various metabolic disorders and diseases. Both pre-pregnancy and maternal obesity can have long-term consequences on offspring health. Furthermore, consuming an HFD in adulthood significantly increases the risk of obesity and metabolic d...

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Main Authors: Suleyma Oliveira Costa, Wenicios Ferreira Chaves, Priscilla Karla Fernandes Lopes, Iracema M. Silva, Beatriz Burguer, Leticia M. Ignácio-Souza, Adriana Souza Torsoni, Marciane Milanski, Hosana Gomes Rodrigues, Mina Desai, Michael Glenn Ross, Marcio Alberto Torsoni
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Immunology
Subjects:
high fat diet (HFD)
cholinergic
hypothalamus
obesity
muscarinic 1 acetylcholine receptors
DOHaD (Developmental origins of health and disease)
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1273556/full

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