A novel microglia-targeting strategy based on nanoparticle-mediated delivery of miR-26a-5p for long-lasting analgesia in chronic pain

A novel microglia-targeting strategy based on nanoparticle-mediated delivery of miR-26a-5p for long-lasting analgesia in chronic pain

Abstract Accumulating evidence supports the notion that microglia play versatile roles in different chronic pain conditions. However, therapeutic strategies of chronic pain by targeting microglia remain largely overlooked. This study seeks to develop a miRNA-loaded nano-delivery system by targeting...

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Bibliographic Details
Main Authors: Yitian Lu, Shuai Liu, Peng Wang, Xiangna Guo, Zaisheng Qin, Honghao Hou, Tao Tao
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Journal of Nanobiotechnology
Subjects:
MG1
Nanoparticles
Chronic pain
Microglia
Analgesia
Online Access:https://doi.org/10.1186/s12951-024-02420-9

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