Stimulator of IFN genes mediates neuroinflammatory injury by suppressing AMPK signal in experimental subarachnoid hemorrhage

Stimulator of IFN genes mediates neuroinflammatory injury by suppressing AMPK signal in experimental subarachnoid hemorrhage

Abstract Background Neuroinflammation is closely associated with the poor prognosis in subarachnoid hemorrhage (SAH) patients. This study was aimed to determine the role of stimulator of IFN genes (STING), an essential regulator to innate immunity, in the context of SAH. Methods A total of 344 male...

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Main Authors: Yucong Peng, Jianfeng Zhuang, Guangyu Ying, Hanhai Zeng, Hang Zhou, Yang Cao, Huaijun Chen, Chaoran Xu, Xiongjie Fu, Hangzhe Xu, Jianru Li, Shenglong Cao, Jingyin Chen, Chi Gu, Feng Yan, Gao Chen
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Journal of Neuroinflammation
Subjects:
Subarachnoid hemorrhage
STING
Microglia
Neuroinflammation
Online Access:http://link.springer.com/article/10.1186/s12974-020-01830-4

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