Association between COVID-19 Vaccine Side Effects and Body Mass Index in Spain
COVID-19 vaccines have shown high efficacy, with most side effects being mild–moderate and more frequently reported by females and people at younger ages. Since no studies have assessed the impact that weight status could have on the reported adverse reactions, we aim to study the association betwee...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-11-01
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| Series: | Vaccines |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-393X/9/11/1321 |
| _version_ | 1797508323364306944 |
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| author | Isabel Iguacel Aurelio Luna Maldonado Aurelio Luna Ruiz-Cabello Marta Casaus Luis Alberto Moreno Begoña Martínez-Jarreta |
| author_facet | Isabel Iguacel Aurelio Luna Maldonado Aurelio Luna Ruiz-Cabello Marta Casaus Luis Alberto Moreno Begoña Martínez-Jarreta |
| author_sort | Isabel Iguacel |
| collection | DOAJ |
| description | COVID-19 vaccines have shown high efficacy, with most side effects being mild–moderate and more frequently reported by females and people at younger ages. Since no studies have assessed the impact that weight status could have on the reported adverse reactions, we aim to study the association between weight status and reported side effects. We included data on 2136 adults from an online survey conducted from 6 May to 9 June 2021. The questionnaire was filled in by participants over Google forms. Generalized Linear Mixed Models were used. A higher risk of presenting fever ≥38°, vomiting, diarrhea and chills was found in those with a non-overweight status compared to those overweight after adjusting for age, sex, education, medication to prevent/relieve post-vaccination effects and vaccine administered. When adjusting, most of the significant effects, in the association between side effects of the COVID-19 vaccine and weight status, did not remain significant. In conclusion, a non-overweight status was associated with a higher risk of presenting fever ≥38°, vomiting, diarrhea and chills compared to those overweight. Nevertheless, most of the reported side effects to COVID-19 vaccine were not associated with a higher risk of presenting more adverse effects, and individual differences were determined by sex and age. |
| first_indexed | 2024-03-10T05:00:29Z |
| format | Article |
| id | doaj.art-c0de24d36791409583c373aa57a3377a |
| institution | Directory Open Access Journal |
| issn | 2076-393X |
| language | English |
| last_indexed | 2024-03-10T05:00:29Z |
| publishDate | 2021-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Vaccines |
| spelling | doaj.art-c0de24d36791409583c373aa57a3377a2023-11-23T01:53:03ZengMDPI AGVaccines2076-393X2021-11-01911132110.3390/vaccines9111321Association between COVID-19 Vaccine Side Effects and Body Mass Index in SpainIsabel Iguacel0Aurelio Luna Maldonado1Aurelio Luna Ruiz-Cabello2Marta Casaus3Luis Alberto Moreno4Begoña Martínez-Jarreta5Faculty of Health Sciences, University of Zaragoza, 50009 Zaragoza, SpainDepartment of Socio-sanitary Sciences, University of Murcia, 30100 Murcia, SpainDepartment of Socio-sanitary Sciences, University of Murcia, 30100 Murcia, SpainFaculty of Health Sciences, University of Zaragoza, 50009 Zaragoza, SpainFaculty of Health Sciences, University of Zaragoza, 50009 Zaragoza, SpainInstituto de Investigación Sanitaria Aragón, 50009 Zaragoza, SpainCOVID-19 vaccines have shown high efficacy, with most side effects being mild–moderate and more frequently reported by females and people at younger ages. Since no studies have assessed the impact that weight status could have on the reported adverse reactions, we aim to study the association between weight status and reported side effects. We included data on 2136 adults from an online survey conducted from 6 May to 9 June 2021. The questionnaire was filled in by participants over Google forms. Generalized Linear Mixed Models were used. A higher risk of presenting fever ≥38°, vomiting, diarrhea and chills was found in those with a non-overweight status compared to those overweight after adjusting for age, sex, education, medication to prevent/relieve post-vaccination effects and vaccine administered. When adjusting, most of the significant effects, in the association between side effects of the COVID-19 vaccine and weight status, did not remain significant. In conclusion, a non-overweight status was associated with a higher risk of presenting fever ≥38°, vomiting, diarrhea and chills compared to those overweight. Nevertheless, most of the reported side effects to COVID-19 vaccine were not associated with a higher risk of presenting more adverse effects, and individual differences were determined by sex and age.https://www.mdpi.com/2076-393X/9/11/1321SARS CoV-2vaccinationoverweightobesityvaccine adverse events |
| spellingShingle | Isabel Iguacel Aurelio Luna Maldonado Aurelio Luna Ruiz-Cabello Marta Casaus Luis Alberto Moreno Begoña Martínez-Jarreta Association between COVID-19 Vaccine Side Effects and Body Mass Index in Spain Vaccines SARS CoV-2 vaccination overweight obesity vaccine adverse events |
| title | Association between COVID-19 Vaccine Side Effects and Body Mass Index in Spain |
| title_full | Association between COVID-19 Vaccine Side Effects and Body Mass Index in Spain |
| title_fullStr | Association between COVID-19 Vaccine Side Effects and Body Mass Index in Spain |
| title_full_unstemmed | Association between COVID-19 Vaccine Side Effects and Body Mass Index in Spain |
| title_short | Association between COVID-19 Vaccine Side Effects and Body Mass Index in Spain |
| title_sort | association between covid 19 vaccine side effects and body mass index in spain |
| topic | SARS CoV-2 vaccination overweight obesity vaccine adverse events |
| url | https://www.mdpi.com/2076-393X/9/11/1321 |
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