Presence of Candida spp. in the oral cavity of heart transplantation patients
Candida spp. can lead to infections or even fungal sepsis particularly among immunocompromized individuals. OBJECTIVE: The aim of the present study was to analyze the presence of Candida spp. among patients subjected to orthotopic heart transplantation. MATERIAL AND METHODS: Oral rinses from 50 pati...
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| Format: | Article |
| Language: | English |
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University of São Paulo
2011-02-01
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| Series: | Journal of Applied Oral Science |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572011000100003 |
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| author | Patrícia Monteiro Ribeiro Fernando Bacal Cristiane Yumi Koga-Ito Juliana Campos Junqueira Antonio Olavo Cardoso Jorge |
| author_facet | Patrícia Monteiro Ribeiro Fernando Bacal Cristiane Yumi Koga-Ito Juliana Campos Junqueira Antonio Olavo Cardoso Jorge |
| author_sort | Patrícia Monteiro Ribeiro |
| collection | DOAJ |
| description | Candida spp. can lead to infections or even fungal sepsis particularly among immunocompromized individuals. OBJECTIVE: The aim of the present study was to analyze the presence of Candida spp. among patients subjected to orthotopic heart transplantation. MATERIAL AND METHODS: Oral rinses from 50 patients subjected to orthotopic heart transplantation, aged 13 to 70 years, 40 males and 10 females, were examined. Sex-age-oral conditions matched-control included 50 individuals who were not subjected to any kind of transplantation and were not immunocompromized for any other reason. Counts of yeasts were expressed as median values of logarithm of cfu/mL and were statistically compared by Mann-Whitney's test. The heart transplant and control groups were compared for the presence of Candida spp. by chi-square test (p<0.05). RESULTS: The results showed statistically significant difference (p=0.001) in the prevalence of Candida spp. between the transplantation and control groups. Counts of yeasts (cfu/mL) in the transplanted group were significantly higher than in the control group (p=0.005). Candida albicans was the most prevalent species isolated from both groups. CONCLUSIONS: It was concluded that Candida yeast counts were higher in the heart transplant recipients than in the controls. There was higher variation of Candida species among the heart transplant patients and the most frequently isolated samples were: Candida albicans, Candida glabrata and Candida tropicalis. Isolates of Candida dubliniensis was not found in either of the groups. |
| first_indexed | 2024-12-14T20:49:12Z |
| format | Article |
| id | doaj.art-c0df8e6e113e40e18047848a04a01cc5 |
| institution | Directory Open Access Journal |
| issn | 1678-7757 1678-7765 |
| language | English |
| last_indexed | 2024-12-14T20:49:12Z |
| publishDate | 2011-02-01 |
| publisher | University of São Paulo |
| record_format | Article |
| series | Journal of Applied Oral Science |
| spelling | doaj.art-c0df8e6e113e40e18047848a04a01cc52022-12-21T22:47:52ZengUniversity of São PauloJournal of Applied Oral Science1678-77571678-77652011-02-0119161010.1590/S1678-77572011000100003Presence of Candida spp. in the oral cavity of heart transplantation patientsPatrícia Monteiro RibeiroFernando BacalCristiane Yumi Koga-ItoJuliana Campos JunqueiraAntonio Olavo Cardoso JorgeCandida spp. can lead to infections or even fungal sepsis particularly among immunocompromized individuals. OBJECTIVE: The aim of the present study was to analyze the presence of Candida spp. among patients subjected to orthotopic heart transplantation. MATERIAL AND METHODS: Oral rinses from 50 patients subjected to orthotopic heart transplantation, aged 13 to 70 years, 40 males and 10 females, were examined. Sex-age-oral conditions matched-control included 50 individuals who were not subjected to any kind of transplantation and were not immunocompromized for any other reason. Counts of yeasts were expressed as median values of logarithm of cfu/mL and were statistically compared by Mann-Whitney's test. The heart transplant and control groups were compared for the presence of Candida spp. by chi-square test (p<0.05). RESULTS: The results showed statistically significant difference (p=0.001) in the prevalence of Candida spp. between the transplantation and control groups. Counts of yeasts (cfu/mL) in the transplanted group were significantly higher than in the control group (p=0.005). Candida albicans was the most prevalent species isolated from both groups. CONCLUSIONS: It was concluded that Candida yeast counts were higher in the heart transplant recipients than in the controls. There was higher variation of Candida species among the heart transplant patients and the most frequently isolated samples were: Candida albicans, Candida glabrata and Candida tropicalis. Isolates of Candida dubliniensis was not found in either of the groups.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572011000100003CandidaHeart transplantationOralFungal infections |
| spellingShingle | Patrícia Monteiro Ribeiro Fernando Bacal Cristiane Yumi Koga-Ito Juliana Campos Junqueira Antonio Olavo Cardoso Jorge Presence of Candida spp. in the oral cavity of heart transplantation patients Journal of Applied Oral Science Candida Heart transplantation Oral Fungal infections |
| title | Presence of Candida spp. in the oral cavity of heart transplantation patients |
| title_full | Presence of Candida spp. in the oral cavity of heart transplantation patients |
| title_fullStr | Presence of Candida spp. in the oral cavity of heart transplantation patients |
| title_full_unstemmed | Presence of Candida spp. in the oral cavity of heart transplantation patients |
| title_short | Presence of Candida spp. in the oral cavity of heart transplantation patients |
| title_sort | presence of candida spp in the oral cavity of heart transplantation patients |
| topic | Candida Heart transplantation Oral Fungal infections |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572011000100003 |
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