Increased Incidence of Pediatric Diabetic Ketoacidosis After COVID-19: A Two-Center Retrospective Study in Korea
Min Jeong Han,1 Jun Ho Heo2 1Department of Pediatrics, Chonbuk National University Hospital, Jeonju, 54907, Korea; 2Department of Emergency Medicine, Wonkwang National University Hospital, Iksan, 54887, KoreaCorrespondence: Jun Ho HeoDepartment of Emergency Medicine, Wonkwang National University Hos...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Dove Medical Press
2021-02-01
|
| Series: | Diabetes, Metabolic Syndrome and Obesity |
| Subjects: | |
| Online Access: | https://www.dovepress.com/increased-incidence-of-pediatric-diabetic-ketoacidosis-after-covid-19--peer-reviewed-article-DMSO |
| _version_ | 1797718698898751488 |
|---|---|
| author | Han MJ Heo JH |
| author_facet | Han MJ Heo JH |
| author_sort | Han MJ |
| collection | DOAJ |
| description | Min Jeong Han,1 Jun Ho Heo2 1Department of Pediatrics, Chonbuk National University Hospital, Jeonju, 54907, Korea; 2Department of Emergency Medicine, Wonkwang National University Hospital, Iksan, 54887, KoreaCorrespondence: Jun Ho HeoDepartment of Emergency Medicine, Wonkwang National University Hospital, 895, Muwang-Ro, Iksan, 54887, KoreaTel +82-63-8591150Fax +82-63-8592129Email tesaza22@hanmail.netPurpose: We evaluated the clinical characteristics and severity of diabetic ketoacidosis (DKA) in children before and after the coronavirus disease 2019 (COVID-19) outbreak to identify its indirect effects on DKA incidence.Patients and Methods: This retrospective study included 19 children with DKA admitted to the emergency room (ER) in two centers in Jeonbuk province, Korea during the first 6 months of the year from 2017 to 2020. Data were collected on age, height, body weight, clinical symptoms, diabetic mellitus (DM) type, and laboratory findings. DKA severity was based on the presence of acute kidney injury, cerebrovascular accident, and altered mental status. The ratio of patients with DKA in all pediatric patients who visited the study ERs and in the Jeonbuk population was also determined.Results: There were no differences in anthropometric characteristics and complication rates between the pre-COVID-19 and COVID-19 periods; however, the rate of polydipsia was significantly higher in the COVID-19 period. All seven patients admitted during the COVID-19 pandemic (100%) had polydipsia and polyuria and were newly diagnosed with DM. The rate of pediatric patients with DKA admitted to the ER in 2020 (0.459%) was more than twice the mean rate of 0.206% for the four-year period. The incidence of DKA in the Jeonbuk population (0.00141%) also exceeded the mean rate (0.0009%).Conclusion: The incidence of pediatric DKA might be higher due to the indirect effect of COVID-19 pandemic. Physicians should be aware of nonspecific symptoms related to DKA in children admitted to the ER.Keywords: coronavirus disease 2019, diabetes, diabetic ketoacidosis, pediatric diabetes |
| first_indexed | 2024-03-12T08:54:11Z |
| format | Article |
| id | doaj.art-c0e06912518742529c4502cf802639e7 |
| institution | Directory Open Access Journal |
| issn | 1178-7007 |
| language | English |
| last_indexed | 2024-03-12T08:54:11Z |
| publishDate | 2021-02-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Diabetes, Metabolic Syndrome and Obesity |
| spelling | doaj.art-c0e06912518742529c4502cf802639e72023-09-02T16:11:18ZengDove Medical PressDiabetes, Metabolic Syndrome and Obesity1178-70072021-02-01Volume 1478379062371Increased Incidence of Pediatric Diabetic Ketoacidosis After COVID-19: A Two-Center Retrospective Study in KoreaHan MJHeo JHMin Jeong Han,1 Jun Ho Heo2 1Department of Pediatrics, Chonbuk National University Hospital, Jeonju, 54907, Korea; 2Department of Emergency Medicine, Wonkwang National University Hospital, Iksan, 54887, KoreaCorrespondence: Jun Ho HeoDepartment of Emergency Medicine, Wonkwang National University Hospital, 895, Muwang-Ro, Iksan, 54887, KoreaTel +82-63-8591150Fax +82-63-8592129Email tesaza22@hanmail.netPurpose: We evaluated the clinical characteristics and severity of diabetic ketoacidosis (DKA) in children before and after the coronavirus disease 2019 (COVID-19) outbreak to identify its indirect effects on DKA incidence.Patients and Methods: This retrospective study included 19 children with DKA admitted to the emergency room (ER) in two centers in Jeonbuk province, Korea during the first 6 months of the year from 2017 to 2020. Data were collected on age, height, body weight, clinical symptoms, diabetic mellitus (DM) type, and laboratory findings. DKA severity was based on the presence of acute kidney injury, cerebrovascular accident, and altered mental status. The ratio of patients with DKA in all pediatric patients who visited the study ERs and in the Jeonbuk population was also determined.Results: There were no differences in anthropometric characteristics and complication rates between the pre-COVID-19 and COVID-19 periods; however, the rate of polydipsia was significantly higher in the COVID-19 period. All seven patients admitted during the COVID-19 pandemic (100%) had polydipsia and polyuria and were newly diagnosed with DM. The rate of pediatric patients with DKA admitted to the ER in 2020 (0.459%) was more than twice the mean rate of 0.206% for the four-year period. The incidence of DKA in the Jeonbuk population (0.00141%) also exceeded the mean rate (0.0009%).Conclusion: The incidence of pediatric DKA might be higher due to the indirect effect of COVID-19 pandemic. Physicians should be aware of nonspecific symptoms related to DKA in children admitted to the ER.Keywords: coronavirus disease 2019, diabetes, diabetic ketoacidosis, pediatric diabeteshttps://www.dovepress.com/increased-incidence-of-pediatric-diabetic-ketoacidosis-after-covid-19--peer-reviewed-article-DMSOcoronavirus disease 2019diabetesdiabetic ketoacidosispediatric diabetes |
| spellingShingle | Han MJ Heo JH Increased Incidence of Pediatric Diabetic Ketoacidosis After COVID-19: A Two-Center Retrospective Study in Korea Diabetes, Metabolic Syndrome and Obesity coronavirus disease 2019 diabetes diabetic ketoacidosis pediatric diabetes |
| title | Increased Incidence of Pediatric Diabetic Ketoacidosis After COVID-19: A Two-Center Retrospective Study in Korea |
| title_full | Increased Incidence of Pediatric Diabetic Ketoacidosis After COVID-19: A Two-Center Retrospective Study in Korea |
| title_fullStr | Increased Incidence of Pediatric Diabetic Ketoacidosis After COVID-19: A Two-Center Retrospective Study in Korea |
| title_full_unstemmed | Increased Incidence of Pediatric Diabetic Ketoacidosis After COVID-19: A Two-Center Retrospective Study in Korea |
| title_short | Increased Incidence of Pediatric Diabetic Ketoacidosis After COVID-19: A Two-Center Retrospective Study in Korea |
| title_sort | increased incidence of pediatric diabetic ketoacidosis after covid 19 a two center retrospective study in korea |
| topic | coronavirus disease 2019 diabetes diabetic ketoacidosis pediatric diabetes |
| url | https://www.dovepress.com/increased-incidence-of-pediatric-diabetic-ketoacidosis-after-covid-19--peer-reviewed-article-DMSO |
| work_keys_str_mv | AT hanmj increasedincidenceofpediatricdiabeticketoacidosisaftercovid19atwocenterretrospectivestudyinkorea AT heojh increasedincidenceofpediatricdiabeticketoacidosisaftercovid19atwocenterretrospectivestudyinkorea |