Effect of Gene-Based Warfarin Dosing on Anticoagulation Control and Clinical Events in a Real-World Setting

Effect of Gene-Based Warfarin Dosing on Anticoagulation Control and Clinical Events in a Real-World Setting

The cytochrome P450 2C9 and vitamin K epoxide reductase complex subunit 1 genotypes are associated with anticoagulation control and the clinical events in warfarin therapy. However, the clinical utility of gene-based warfarin dosing (GBWD) is controversial. We compared the anticoagulation control an...

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Bibliographic Details
Main Authors: Jinhua Zhang, Tingting Wu, Wenjun Chen, Jinglan Fu, Xiaotong Xia, Liangwan Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Pharmacology
Subjects:
pharmacogenetics
CYP2C9
precision medicine
warfarin
VKORC1
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.01527/full

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